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CRYSTALLOGRAPHIC STRUCTURE OF THE ANDROGEN RECEPTOR LIGAND BINDING DOMAIN PCT/US2000/028495
[WEINMANN, Roberto, EINSPAHR, Howard, M., KRYSTEK, Stanley, R., Jr., SACK, John, S., SALVATI, Mark, E., TOKARSKI, John, S., WANG, Chihuei, ATTAR, Ricardo, M.] Route 206 and Province Line Road P.O. Box 4000 Princeton, NJ 08543;98 Bayard Lane Princeton, NJ 08540;67 Green Avenue Lawrenceville, NJ 08648;15 Back Brook Road Ringoes, NJ 08551;50 Merion Place Lawrenceville, NJ 08648;9 Tracey Drive Lawrenceville, NJ 08648;11 Walker Drive Princeton, NJ 08540;916 Deer Creek Drive Plainsboro, NJ 08536;10 Santina Court Lawrenceville, NJ 08648 The first crystal structure of the androgen receptor ligand binding domain has been determined to 2.0 angstrom resolution. Disclosed are the coordinates for the crystal structure, and methods for determining agonists, partial agonists, antagonists, partial antagonists, and selective androgen receptors modulators (SARMS) of the androgen receptor.
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METHOD AND APPARATUS FOR CONTROLLED PHOTOELUTION PCT/US1998/017108
[AFFLECK, Rhett, L., HOBBS, Doug, FEYGIN, Ilya, KIRK, Gregory, L., CONNELLY, James, A., ZHAO, Ning, MUELLER, James, P., KIESELBACH, Peter] CN 5350 Princeton, NJ 08543;41 Green Avenue Lawrenceville, NJ 08648;843 Garfield Avenue Lansdale, PA 19446;853 Hillside Avenue Mountainside, NJ 07092;23 Jefferson Road Winchester, MA 01890;212 Share Drive Yardley, PA 19067;3 Elm Court Lawrenceville, NJ 08648;89 Princeton Arms North One Cranbury, NJ 08512;344 Marienstein Road Upper Black Eddy, PA 18972 A method for photoeluting photocleavable linker-attached chemical compounds, and an apparatus suitable for implementing the method, are disclosed. According to the method, photocleavable linker-attached library compounds are photoeluted from solid support media under conditions of controlled light exposure and controlled temperature. An apparatus suitable for carrying out the present photoelution method includes means for substantially evenly illuminating the photocleavable linker, means for controlling illumination time and intensity, and means for controlling sample temperature.
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LOW VOC COALESCING AGENTS PCT/US2009/000615
[ZHOU, Lichang, PAKENHAM, Derek, RUIZ, Jose, CHEN, Pu, AYMES, Charles, MILLER, Keri, Marie, KOLTISKO, Bernard] 40, rue de la Haie Coq F-93306 Aubervilliers;8 Yorkshire Village Road Lawrenceville, NJ 08648;3029 E. State Street Ext. Hamilton, NJ 08619;36 Groom Street Burlington, NJ 08016;Block 51, #07-02 Hillview Avenue Hillington Green 669565;13 Marvin Road Monmouth Junction, NJ 08852;1808 Kuser Road, Apt. 3 Hamilton, NJ 08690;482 Kings Road Yardley, PA 19067 A coalescent composition for coating compositions such as paints, adhesives, and coatings comprising a blend of dibasic esters, specifically (i) esters of adipic, glutaric, and/or succinic diacids and/or (ii) esters of isomers of adipic acid have advantages, including efficiency and low VOC.
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