[YANG, Chen 杨晨, YANG, Chen 杨晨, QIN, Bingbing 秦兵兵, YANG, Chen 杨晨, QIN, Bingbing 秦兵兵, ZHENG, Yi 郑毅, YANG, Chen 杨晨, QIN, Bingbing 秦兵兵, ZHENG, Yi 郑毅, LIU, Charlie 刘驰, YANG, Chen 杨晨, QIN, Bingbing 秦兵兵, ZHENG, Yi 郑毅, LIU, Charlie 刘驰, LI, Naiqiang 李乃强, YANG, Chen 杨晨, QIN, Bingbing 秦兵兵, ZHENG, Yi 郑毅, LIU, Charlie 刘驰, LI, Naiqiang 李乃强, LIU, Xiucai 刘修才] 4th Floor, Building 5, 1690 Cailun Road, Zhangjiang Hitech Park, Pudong New District 中国上海市浦东新区张江高科技园区蔡伦路1690号5幢4楼, Shanghai 201203Shanghai 201203;4th Floor, Harbour Centre, P.O.Box 613, George Town 英国英属西印度群岛开曼群岛大开曼岛乔治敦城哈勃中心四楼, British West IndiesGrand Cayman, Cayman Islands, British West Indies The present invention provides a nylon salt preparation method. The method comprises the following steps: mixing 1,5-pentanediamine, water and diacid at the temperature of 65°C to 120°C, so as to prepare the nylon salt, the weight of water accounting for 2 wt% to 12 wt% of the total weight of the 1,5-pentanediamine and the diacid. The present invention further provides a nylon salt. The nylon salt preparation method provided in the present invention avoids the incomplete reaction between the 1,5-pentanediamine and the diacid due to the solid state of the nylon salt during the preparation process, significantly improves the reaction rate, greatly reduces the reaction time, enables the residual amounts of the diamine and the diacid in the nylon salt to be at a very low level, and makes the finally obtained nylon salt product in a solid state, thereby facilitating the storage and transport of the nylon salt product.

[CHEN, Zheng-yi, CHEN, Zheng-yi, LIU, David] 325 Charles Street, 6th FloorBoston, MA 02114 Compositions are described for direct protein delivery into multiple cell types in the mammalian inner ear. The compositions are used to deliver protein(s) (such as gene editing factors) editing of genetic mutations associated with deafness or associated disorders thereof. The delivery of genome editing proteins for gene editing and correction of genetic mutations protect or restore hearing from genetic deafness. Methods of treatment include the intracellular delivery of these molecules to a specific therapeutic target.

[CHEN, Zheng-Yi, CHEN, Zheng-Yi, LIU, David] 325 Charles Street, 6th FloorBoston, MA 02114 A chimeric molecule of one or more proteins or peptides fused, complexed or linked to one or more anionic molecules. Efficient in vitro and in vivo delivery is attained by encapsulating these molecules in cationic lipids or cationic liposomes. Methods of treatment include the intracellular delivery of these molecules to a specific therapeutic target.

[YEH CHUN-HAO, HUNG ZHENG-YI, LIN H/JHIH-WEI, CHEN XIN-HAN, WANG ZHENG-YI, CHIANG HUI-FEN, YAN SHU-FEN, HUANG DAO-SHINN] TW An innovative vehicle-mounted real-time heart rate and blood oxygen measurement system designed to ensure the safety of middle-aged and elderly drivers. This system uses the advanced heart rate detection component MAX30100, which can instantly detect heart rate and blood oxygen level when the driver\'s finger is placed above it. These data are connected to the cloud through the IFTTT (IF THIS THEN THAT) system and then projected using APP Inventor, realizing real-time transmission and monitoring of data. When the driver feels unwell, the system can immediately measure the heart rate and blood oxygen level, and issue an alarm when necessary to remind the driver to take timely action.

[JIA, Boyu 贾博宇, YIN, Zhaoyi 尹昭怡, AN, Xinyi 安心怡, GU, Shuai 顾帅, CHEN, Chen 陈晨, LIU, Tianyu 刘天宇, ZHENG, Yi 郑义, YE, Jianing 叶家宁, CHEN, Junchao 陈俊超, CHEN, Guodong 陈国栋, GUO, Yongsheng 郭永胜] Room 203 And 204, Floor 2, Building 1 中国上海市闵行区园美路58号1幢2层203、204室, Shanghai 200241No. 58, Yuanmei RoadMinhang District, Shanghai 200241;No.2 Xingang Road, Zhangwan Town 中国福建省宁德市蕉城区漳湾镇新港路2号, Fujian 352100Jiaocheng DistrictNingde, Fujian 352100 Provided are a perovskite thin film and a preparation method therefor, a perovskite cell and an electric device. The perovskite thin film comprises: a perovskite substrate layer; and a plurality of nano-protrusions, which are distributed at intervals on at least one surface of the perovskite substrate layer.

[CHEN, Jinqing, CHEN, Dajun, CHEN, Junhuang, WU, Meiqiong, WU, Songgang, HUANG, Jianzhong, ZHENG, Yi] Xinyang Industrial Area, Haicang District Xiamen, Fujian 361022;Xinyang Industrial Area, Haicang District Xiamen, Fujian 361022;Xinyang Industrial Area, Haicang District Xiamen, Fujian 361022;Xinyang Industrial Area, Haicang District Xiamen, Fujian 361022;Xinyang Industrial Area, Haicang District Xiamen, Fujian 361022;Xinyang Industrial Area, Haicang District Xiamen, Fujian 361022;Xinyang Industrial Area, Haicang District Xiamen, Fujian 361022;Xinyang Industrial Area, Haicang District Xiamen, Fujian 361022 A fermentation culture method for solid material mother culture in production of coenzyme Q10. The strain used in this method is Rhodobacter sphaeroides. Slant strain is used for passaging, and culturing in slant medium; after steam cooking and atmospheric drying, the solid material medium is subpackaged and sterilized, wherein said solid material medium comprises solid material components and liquid components; prepared by mixing fresh slant Rhodobacter sphaeroides strain with sterile water, bacterial suspension is added into the solid material medium, and used as mother culture of first fermentation after culturing. The method of the present invention can raise fermentation level of coenzyme Q10, save fermentation series number, shorten production cycle, simplify production link, and lower production cost.

[ZHUANG ZHAO-QI, JIANG BO-YUAN, CHEN YU-XIN, CHEN JIA-YUN, ZHENG YI-XIANG, CHEN YU-XIU, HU LIU-LI] TW A food synchronous rotating feeding and blending spinning device is a continuous operator that can feed and rewind in an uninterrupted manner. The device includes an adjustable feeding support mechanism, a feeding mechanism, a hot-melt centrifugal spinning body and a control mechanism. In this way, the proposed adjustable feeding support mechanism can be applied to the size range of the cotton candy machines in the current industry, which can not only adjust the height but also adjust the diameter. Accordingly, the proposed adjustable feeding support mechanism can be applied to the existing cotton candy machines of different manufacturers through simple disassembly and assembly and is very convenient. Furthermore, by omitting the bulky full cover, the appearance is open, refreshing and bright, and the overall appearance is beautiful. This invention can continuously feed and rewind to achieve the effect of continuous production. This invention is very suitable for use in business places that require mass, stable and fast supply. Moreover, through replacing the lower bulky turntable by rotating the upper feeding hopper to feed, the same spinning, binding and blending effects can be obtained without a binding agent, so as to have the advantages of simple structure, light weight, simple production and convenient cleaning..

[YIN, Zhaoyi 尹昭怡, AN, Xinyi 安心怡, JIA, Boyu 贾博宇, CHEN, Junchao 陈俊超, GUO, Yongsheng 郭永胜, CHEN, Chen 陈晨, LIU, Tianyu 刘天宇, ZHENG, Yi 郑义, GU, Shuai 顾帅, YE, Jianing 叶家宁] Room 203 and 204, Floor 2, Building 1, No. 58, Yuanmei Road 中国上海市闵行区园美路58号1幢2层203、204室, Shanghai 200241Minhang District, Shanghai 200241;No.2 Xingang Road, Zhangwan Town, Jiaocheng District, Ningde City 中国福建省宁德市蕉城区漳湾镇新港路2号, Fujian 352100Ningde, Fujian 352100 The present application relates to a compound, a perovskite solar cell and an electric device. The compound provided in the present application is applied to a hole transport layer and a perovskite layer of a perovskite solar cell or between the two layers; and a chain structure of a thiophene group or a chain structure of a benzothiophene group is used as the backbone of the compound, and an electron-rich group or an electron-withdrawing group is connected to the chain structure by means of a C0-C8 alkane group. The compound can match perovskite materials having a variety of energy levels when being applied to a perovskite solar cell. The present application relates to a compound, a perovskite solar cell and an electric device. The compound provided in the present application is applied to a hole transport layer and a perovskite layer of a perovskite solar cell or between the two layers; and a chain structure of a thiophene group or a chain structure of a benzothiophene group is used as the backbone of the compound, and an electron-rich group or an electron-withdrawing group is connected to the chain structure by means of a C0-C8 alkane group. The compound can match perovskite materials having a variety of energy levels when being applied to a perovskite solar cell.

[ZHUANG ZHAO-QI, JIANG BO-YUAN, CHEN YU-XIN, CHEN JIA-YUN, ZHENG YI-XIANG, CHEN YU-XIU, HU LIU-LI] TW

[FENG, Zhiqiang, CHEN, Xiaoguang, YANG, Yang, ZHOU, Chuan, LAI, Fangfang, JI, Ming, JIN, Xiaofeng, XUE, Nina, ZHENG, Yi, CHEN, Hao, LI, Ling] No. 1, Xian Nong Tan Street Xuanwu District, Beijing 100050, CN The present invention discloses a phenylate derivative, a preparation method therefor, and a pharmaceutical composition and uses thereof. Specifically, the invention relates to phenylate derivatives represented by formula (I), a pharmaceutically-acceptable salt thereof, a stereoisomer thereof, a preparation method therefor, a pharmaceutical composition containing the one or more compounds, and uses of the compounds in treating diseases related to PD-1/PD-L1 signal channels, such as cancers, infectious diseases and autoimmune diseases. ＜chemistry id="chema01" num="0001"＞＜img id="ia01" file="imga0001.tif" wi="39" he="27" img-content="chem" img-format="tif" /＞＜/chemistry＞