in:(HONG-BO ZHANG)

Pharmaceutical composition for treating myocardial ischemia and preparation method thereof TW111135318A
[SUN HE, YAN KAI-JING, MA XIAO-HUI, ZHANG SHUN-NAN, HE YI, XIONG HAO-SHU, ZHENG YONG-FENG, LI XIN-XIN, ZHANG HONG-BO, LI YAN-MEI, WANG JING, WEN TIAN-TIAN, HUO ZHI-PENG, FAN LI-JUN, SUN WEI, WANG JIAN-CHUN, CAI NAN, YANG RUI, ZHANG JING-JING] CN Disclosed is a pharmaceutical composition for treating myocardial ischemia, comprising 250-700 parts by weight of a Salvia miltiorrhizax radix et rhizome medicinal material, 50-150 parts by weight of a Notoginseng radix et rhizome medicinal material, 3-9 parts by weight of borneol and 25-100 parts by weight of ranolazine. The pharmaceutical composition is applied to the preparation of a drug for preventing and/or treating myocardial ischemia.
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Preparation method for traditional chinese medicine micro drop pill and traditional chinese medicine micro drop pill prepared by using the method TW103124003A
[YAN XI-JUN, WU NAI-FENG, YAN KAI-JING, SUN XIAO-BING, ZHANG SHUN-NAN, YE ZHENG-LIANG, DONG HAI-OU, ZHANG HONG-BO, ZHANG WEN-SHENG, ZHOU LI-HONG, LI CHEN-MING, CHEN CONG, LIU XIAO-FENG, WANG SHI-QING, RONG CHANG-SHENG, ZHENG YONG-FENG, FAN LI-JUN] CN A preparation method for a traditional Chinese medicine micro drop pill and a traditional Chinese medicine micro drop pill prepared by using the method, and in particular, a micro drop pill preparation method that achieves a high drug loading capacity and has a simple preparation process and a high production rate, and a micro drop pill prepared by using the method. Specifically, the drop pill preparation method used comprises the following steps: (1) a material melting step: heating and melting medicine and a drop pill matrix to obtain a molten liquor; (2) a dropping step: delivering the molten liquor to a dripper, and acquiring drops of the molten liquor by means of vibration dropping; and (3) a condensation step: cooling the medicine drops with cooling air, to obtain micro drop pills.
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INTELLIGENT CONTAINER YARD SYSTEM PCT/CN2018/081640
[GUO ZHAO, Zhang, WEI, Zhao, HONG BO, Zhang, XIN JIE, Zhang] 2F, No. 199, Wending Road, Xuhui DistrictShanghai 200030 An intelligent container yard system is characterized by comprising one or more multi-layer storage units, wherein each multi-layer storage unit comprises multiple layers of container yards, storage hoisting devices arranged at the upper parts of each layer of container yards and used for storing or taking out containers, interactive hoisting devices for loading and unloading containers from transport devices, and shuttle vehicles; a stable frame guide rail penetrating through the floor of each layer of yards is vertically arranged on one side of the multiple layers of container yards, the stable frame guide rail is hollow inside, and the storage hoisting devices in the container yards above the first layer hoist or lay down containers through the stable frame guide rail and the hollow part of the stable frame guide rail to the shutter vehicles arranged on the first layer. The system realizes tidy and ordered container stacking and efficient and convenient container storage and fetching, and the whole yard system can be intelligently controlled to realize full-automatic efficient management of containers. An intelligent container yard system is characterized by comprising one or more multi-layer storage units, wherein each multi-layer storage unit comprises multiple layers of container yards, storage hoisting devices arranged at the upper parts of each layer of container yards and used for storing or taking out containers, interactive hoisting devices for loading and unloading containers from transport devices, and shuttle vehicles; a stable frame guide rail penetrating through the floor of each layer of yards is vertically arranged on one side of the multiple layers of container yards, the stable frame guide rail is hollow inside, and the storage hoisting devices in the container yards above the first layer hoist or lay down containers through the stable frame guide rail and the hollow part of the stable frame guide rail to the shutter vehicles arranged on the first layer. The system realizes tidy and ordered container stacking and efficient and convenient container storage and fetching, and the whole yard system can be intelligently controlled to realize full-automatic efficient management of containers.
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P300 inhibitors and use thereof in medicine TW110141376A
[WU HAO, GU WEI, LIN YUAN-WANG, DENG TAO, WANG WEI, WANG DONG, ZHANG RUI-BO, WANG GUO-JIAN, LU JING-HE, LI JIN-HUA, ZHANG HONG-BO, LI YANG, TAO GUANG-XU, LI ZHENG-QING, LAN HONG, WANG JIABING, DING LIE-MING] CN The present invention relates to compounds which have cancer treatment activity, and also relates to a preparation method for such compounds and a pharmaceutical composition comprising same.
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Indole macrocyclic derivatives, a preparation method thereof and medical use thereof TW108135199A
[ZHANG GUO-BAO, FEI HONG-BO, ZHANG XIAO-MIN, HU WEI-MIN, HE FENG, TAO WEI-KANG] CN;CN The present invention relates to indole macrocyclic derivatives, a preparation method thereof and medical use thereof. Specifically, the present invention relates to an indole macrocyclic derivative represented by the general formula (IM), a preparation method thereof, a pharmaceutical composition comprising the same and a use of it as a therapeutic agent, particularly as a MCL-1 inhibitor. The definition of each groups of formula (IM) is as defined in the specification.
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LITHIUM-LOADED COMPOSITE FRAMEWORK MATERIAL, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF PCT/CN2022/133290
[LAI, Yanqing 赖延清, HONG, Bo 洪波, JIANG, Huai 姜怀, LAI, Junquan 赖俊全, WANG, Mengran 王梦然, WANG, Qiyu 王麒羽, LI, Jie 李劼, ZHOU, Yangen 周言根, ZHANG, Zhian 张治安, ZHANG, Kai 张凯, QIN, Furong 覃富荣] No.932 South Lushan Road 中国湖南省长沙市麓山南路932号, Hunan 410083Changsha, Hunan 410083 A lithium-loaded composite framework material, a preparation method therefor, and an application thereof. The lithium-loaded composite framework material is a thin-film encapsulation structure in which a plurality of hollow thin-walled carbon nanospheres are encapsulated; the inner walls of the hollow thin-walled carbon nanospheres are compounded with low lithium precipitation overpotential nanoparticles; a thin film is a high lithium precipitation overpotential film layer; the film layer is single-layer or multilayer; the film layer is selected from a carbon layer, a polymer film layer, a solid electrolyte film layer, an oxide film layer, or a mixed ionic/electronic conductor film layer; the low lithium precipitation overpotential nanoparticle is defined as a simple substance or compound having a lithium reaction potential greater than 0 V; the high lithium precipitation overpotential film layer is defined as a film layer in which an electrodeposition potential of lithium on the surface of the film layer is less than 0 V. Compared with thin films, the inner wall of the lithium-loaded composite framework material has a lower lithium precipitation potential, so that lithium ions are selectively induced into a carbon cavity and are uniformly deposited in the carbon nanospheres, thereby achieving the encapsulation and continuous and uniform deposition/dissolution of lithium metal. A lithium-loaded composite framework material, a preparation method therefor, and an application thereof. The lithium-loaded composite framework material is a thin-film encapsulation structure in which a plurality of hollow thin-walled carbon nanospheres are encapsulated; the inner walls of the hollow thin-walled carbon nanospheres are compounded with low lithium precipitation overpotential nanoparticles; a thin film is a high lithium precipitation overpotential film layer; the film layer is single-layer or multilayer; the film layer is selected from a carbon layer, a polymer film layer, a solid electrolyte film layer, an oxide film layer, or a mixed ionic/electronic conductor film layer; the low lithium precipitation overpotential nanoparticle is defined as a simple substance or compound having a lithium reaction potential greater than 0 V; the high lithium precipitation overpotential film layer is defined as a film layer in which an electrodeposition potential of lithium on the surface of the film layer is less than 0 V. Compared with thin films, the inner wall of the lithium-loaded composite framework material has a lower lithium precipitation potential, so that lithium ions are selectively induced into a carbon cavity and are uniformly deposited in the carbon nanospheres, thereby achieving the encapsulation and continuous and uniform deposition/dissolution of lithium metal.
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AIR SUPPLY AND POWER GENERATION SYSTEM FOR LARGE-SCALE BLAST FURNACE, AND LOAD DISTRIBUTION CONTROL METHOD THEREFOR PCT/CN2024/073153
[HONG, Bo 洪波, LIU, Zhong 刘忠, YANG, Cairong 杨彩茸, LIU, Yongjun 刘拥军, MIN, Yanfeng 闵彦锋, DU, Guodong 杜国栋, SUN, Hongsheng 孙鸿声, CHEN, Yuping 陈余平, ZHENG, Xiuping 郑秀萍, WU, Guang 吴广, YANG, Gang 杨刚, ZHANG, Shengli 张胜利, ZHANG, Li 张立, WANG, Chaoyang 王朝阳, CAO, Pengpeng 曹鹏鹏, LIU, Zhou 刘洲, JIA, Jiangping 贾江平, WANG, Licheng 王力成, LI, Jie 李杰, ZHOU, Qi 周琦, TANG, Li 唐骊] No. 8 South Fenghui Road, High-tech Zone 中国陕西省西安市高新区沣惠南路8号, Shaanxi 710075Xi'an, Shaanxi 710075 The present invention relates to a large-scale metallurgical blast furnace, and particularly relates to an air supply and power generation system for a large-scale blast furnace, and a load distribution control method therefor. In order to solve the technical problem in the prior art of machine units being prone to interlock shutdown, the air supply and power generation system for a large-scale blast furnace of the present invention comprises a 4# axial compressor and a first power unit, and a 5# axial compressor and a second power unit for driving the 5# axial compressor, wherein output ends of the 4# axial compressor and the 5# axial compressor are each connected to a 2# blast furnace and supply gas to the 2# blast furnace, the first power unit comprises a gas waste-heat drive assembly and an electric energy conversion assembly, and the electric energy conversion assembly is configured to drive the 4# axial compressor or generate electricity. Further provided is a load distribution control method based on the system. <
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LITHIUM-LOADED COMPOSITE FRAMEWORK MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF ZA202405029A
[LAI YANQING, HONG BO, JIANG HUAI, LAI JUNQUAN, WANG MENGRAN, WANG QIYU, LI JIE, ZHOU YANGEN, ZHANG ZHIAN, ZHANG KAI, QIN FURONG] CN The present invention provides a lithium-loaded composite framework material, a preparation method therefor, and use thereof. The lithium-loaded composite framework material is a thin-film encapsulation structure in which a plurality of hollow thin-walled carbon nanospheres are encapsulated; the inner walls of the hollow thin-walled carbon nanospheres are compounded with low lithium precipitation overpotential nanoparticles; a thin film is a high lithium precipitation overpotential film layer; the film layer is a single-layer or multilayer; the film layer is selected from a carbon layer, a polymer film layer, a solid electrolyte film layer, an oxide film layer, or ion/electron mixed conductor film layer; the low lithium precipitation overpotential nanoparticle is defined as a simple substance or compound having a lithium reaction potential of greater than 0 V; the high lithium precipitation overpotential film layer is defined as a film layer in which an electrodeposition potential of lithium on the surface is less than 0 V. Compared with the thin film, the inner wall of the lithium-loaded composite framework material in the present invention has a lower lithium precipitation potential, so that lithium ions are selectively induced into a carbon cavity and uniformly deposited in the carbon nanosphere, thereby achieving the encapsulation and continuous and uniform deposition/dissolution of lithium metal.
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MEMORY CELL AND FABRICATION METHOD THEREOF EP17152904.3
[HONG, Bo, ZHANG, Shuai] No. 18, Zhangjiang Road Pudong New Area, Shanghai 201203, CN Memory cells and fabrication methods thereof are provided. An exemplary method includes providing a substrate having a well region; forming a select gate structure, a floating gate structure and a dummy gate structure on a surface of the well region; forming a first lightly doped region, a second lightly doped region and a third lightly doped region in the well region, the first lightly doped region and the second lightly doped region being at two sides of the select gate structure respectively, the second lightly doped region being in between the select gate structure and the floating gate structure, and the third lightly doped region being in between the floating gate structure and the dummy gate structure; and forming bit line region in the first lightly doped region and a source region in the third lightly doped region, the source region being enclosed by the third lightly doped region.
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Excitation radio frequency system of plasma etching machine TW110146816A
[LIU HAI-YANG, LIU XIAO-BO, SUN HONG-BO, GUO SONG, WANG CHENG-YI, ZHANG XIAO, HU DONG-DONG, XU KAIDONG] CN The application is related to the technical field of semiconductor chip production equipment, in particular to an excitation radio frequency system of a plasma etching machine. The plasma etching machine includes a plasma reaction chamber. The excitation radio frequency system includes: a dielectric window, which is configured as the top wall of the plasma reaction chamber; a radio frequency coil, which is arranged above the dielectric window; a heating element, which is attached to the upper surface of the dielectric window and is in direct contact with the dielectric window, the heating element is located between the radio frequency coil and the dielectric window; a homogeneous layer, which is laid on top of the heating element and is in direct contact with the heating element. In this application, the media window and the bottom surface of the air inlet nozzle can be thoroughly cleaned, and the bombardment by-products are pumped away by the bottom air pump set.
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