[Jinming ZHOU, Yuejun ZHANG, Huijie ZHANG, Lijun MA, Xiaojun LV, Haiqin ZHAO, Xiaojiang ZHOU, Shuliang SONG, Wei ZHAO, Yujie SHI, Chaozhi ZHAI] CN Qingdao, Shandong A central traction device for a straddling monorail train includes a traction pin and a traction beam. A central sleeve is provided at the center of the traction beam, and the traction pin is mounted in the central sleeve. An inner cavity of the central sleeve has a corset-shaped structure having large diameters on an upper end and a lower end and a small diameter at a middle part, forming double tapered bevels, and a resilient rubber bush is provided between an inner wall of the central sleeve and the traction pin. The device has a simple and compact overall structure and facilitates connection and separation between the train body and the bogie; by providing the lift assembly, the traction device is fixedly connected to the frame, thus the traction device can be wholly lifted; and operation process and environment of raising and lowering the vehicle are improved.

[Wei Chen, Haiqin Chen, Yongquan Chen, Guangfei Hao, Zhennan Gu, Jianxin Zhao, Hao Zhang, Xiaoyun Huang, Kai Du, Shanshan Zhao] CN Wuxi It relates to a Mortierella alpine ATCC32222 uracil auxotroph strain and a construction method thereof. In the present invention, Mortierella alpine ATCC32222 is used as a material and undergoes gene knockout through an Agrobacterium tumefaciens mediated genetic manipulation technology, to obtain the Mortierella alpine uracil auxotroph. The method is of great significance for the basic theoretic researches of the oil producing fungus Mortierella alpine ATCC32222 and product development.

[Yongquan CHEN, WEL CHEN, GUANGFEI HAO, HAIQIN CHEN, JIANXIN ZHAO, ZHENNAN GU, HAO ZHANG, DANHUI HAO, SHANSHAN ZHAO] CN Wuxi, Jiangsu It relates to a Mortierella alpina recombinant gene expression system, to its construction method and application which is constructed by transformation of M. alpina ATCC 32222 uracil auxotroph strain through A. tumefaciens mediate transformation (ATMT) and is based on the existing uracil auxotrophic strain, through genetic engineering methods to obtain a final phenotype complementary strain to achieve the malic enzyme 1 and malic enzyme 2 overexpression strains.

[TANG, Benzhong, ZHAO, Engui, GUI, Chen, JIANG, Meijuan, DENG, Haiqin, LEUNG, Wai Tung, WANG, Zhiming, ZHAO, Yueyue, KWOK, Tsz Kin, VIGLIANTI, Lucia, XIE, Ni] Clear Water Bay, KowloonHong Kong The present subject matter relates to AIE luminogens for visualization and treatment of cancer, particularly AIE luminogenic probes for cancer cell visualization and discrimination, lysosome-targeting AIEgens for imaging and autophagy visualization, highly fluorescent AIE-active theranostic agents for monitoring drug distribution and having anti-tumor activity to specific cancer cells, probes comprising AIE luminogens for cancer cell imaging and staining, AIE luminogens having clusteroluminogenic features and applications thereof, and methods of preparing thereof. The present subject matter relates to AIE luminogens for visualization and treatment of cancer, particularly AIE luminogenic probes for cancer cell visualization and discrimination, lysosome-targeting AIEgens for imaging and autophagy visualization, highly fluorescent AIE-active theranostic agents for monitoring drug distribution and having anti-tumor activity to specific cancer cells, probes comprising AIE luminogens for cancer cell imaging and staining, AIE luminogens having clusteroluminogenic features and applications thereof, and methods of preparing thereof.

[Wei Chen, Haiqin CHEN, Yongquan CHEN, Guangfei HAO, Zhennan GU, Jianxin ZHAO, Hao ZHANG, Xiaoyun HUANG, Kai DU, Shanshan ZHAO] CN Jiangsu It relates to a Mortierella alpine ATCC32222 uracil auxotroph strain and a construction method thereof. In the present invention, Mortierella alpine ATCC32222 is used as a material and undergoes gene knockout through an Agrobacterium tumefaciens mediated genetic manipulation technology, to obtain the Mortierella alpine uracil auxotroph. The method is of great significance for the basic theoretic researches of the oil producing fungus Mortierella alpine ATCC32222 and product development.

[ZHOU, Jinming, ZHANG, Yuejun, ZHANG, Huijie, MA, Lijun, LV, Xiaojun, ZHAO, Haiqin, ZHOU, Xiaojiang, SONG, Shuliang, ZHAO, Wei, SHI, Yujie, ZHAI, Chaozhi] No.88 Jinhongdong Road Chengyang District, Qingdao City, Shandong 266111, CN

[ZHOU, Jinming 周锦铭, ZHANG, Yuejun 张月军, ZHANG, Huijie 张会杰, MA, Lijun 马利军, LV, Xiaojun 吕晓俊, ZHAO, Haiqin 赵海芹, ZHOU, Xiaojiang 周小江, SONG, Shuliang 宋树亮, ZHAO, Wei 赵伟, SHI, Yujie 史玉杰, ZHAI, Chaozhi 翟超智] No.88 Jinhongdong Road, Chengyang District 中国山东省青岛市城阳区锦宏东路88号, Shandong 266111Qingdao, Shandong 266111 A central traction device for a straddling monorail train comprises a traction pin (9) and a traction beam (10). A central sleeve (22) is disposed at the center of the traction beam (10), the traction pin (9) is mounted in the central sleeve (22), the inner chamber of the central sleeve (22) is of a tightened-waist structure having bigger apertures at the upper end and the lower end and a smaller aperture at the middle part, a biconical inclined plane is formed, and an elastic rubber sleeve is disposed between the inner wall of the central sleeve (22) and the traction pin (9). The device has a simple and compact overall structure, and helps to implement connection and separation between a vehicle body and a bogie; by means of cooperation among the traction beam (10) of the tightened-waist structure, the elastic rubber sleeve and a traction rubber pile (11), transmission of traction force and braking force during operation of a vehicle in function is better implemented, the change of load in a transverse direction and a longitudinal direction as well as loading can also be better adapted, requirements of a larger traction force and a larger load change can be satisfied, and the stability and the comfort during operation of the vehicle are greatly improved.

[Benzhong Tang, Engui Zhao, Chen Gui, Meijuan Jiang, Haiqin Deng, Wai Tung Leung, Zhiming Wang, Yueyue Zhao, Tsz Kin Kwok, Lucia Viglianti, Ni Xie] CN Hong Kong The present subject matter relates to ATE luminogens for visualization and treatment of cancer, particularly AIE luminogenic probes for cancer cell visualization and discrimination, lysosome-targeting AIEgens for imaging and autophagy visualization, highly fluorescent AIE-active theranostic agents for monitoring drug distribution and having anti-tumor activity to specific cancer cells, probes comprising AIE luminogens for cancer cell imaging and staining, AIE luminogens having clusteroluminogenic features and applications thereof, and methods of preparing thereof.

[Benzhong TANG, Engui ZHAO, Chen GUI, Meijuan JIANG, Haiqin DENG, Wai Tung LEUNG, Zhiming WANG, Yueyue ZHAO, Tsz Kin KWOK, Lucia VIGLIANTI, Ni XIE] CN Hong Kong The present subject matter relates to ATE luminogens for visualization and treatment of cancer, particularly AIE luminogenic probes for cancer cell visualization and discrimination, lysosome-targeting AIEgens for imaging and autophagy visualization, highly fluorescent AIE-active theranostic agents for monitoring drug distribution and having anti-tumor activity to specific cancer cells, probes comprising AIE luminogens for cancer cell imaging and staining, AIE luminogens having clusteroluminogenic features and applications thereof, and methods of preparing thereof.

[Jinming Zhou, Yuejun Zhang, Huijie Zhang, Lijun Ma, Xiaojun Lv, Haiqin Zhao, Xiaojiang Zhou, Shuliang Song, Wei Zhao, Yujie Shi, Chaozhi Zhai] CN Qingdao, Shandong A central traction device for a straddling monorail train includes a traction pin and a traction beam. A central sleeve is provided at the center of the traction beam, and the traction pin is mounted in the central sleeve. An inner cavity of the central sleeve has a corset-shaped structure having large diameters on an upper end and a lower end and a small diameter at a middle part, forming double tapered bevels, and a resilient rubber bush is provided between an inner wall of the central sleeve and the traction pin. The device has a simple and compact overall structure and facilitates connection and separation between the train body and the bogie; by providing the lift assembly, the traction device is fixedly connected to the frame, thus the traction device can be wholly lifted; and operation process and environment of raising and lowering the vehicle are improved.