[MITCHELL, Ian S., BLAKE, James, F., XU, Rui, KALLAN, Nicholas C., XIAO, Dengming, SPENCER, Keith Lee, BENCSIK, Josef R.] 3200 Walnut Street, Boulder, CO 80301, US

[MITCHELL, Ian S., BLAKE, James F., XU, Rui, KALLAN, Nicholas C., XIAO, Dengming, SPENCER, Keith Lee, BENCSIK, Josef R., LIANG, Jun, SAFINA, Brian, LI, Jun, CHABOT, Christine, BANKA, Anna.L., WALLACE, Eli. M., SCHLACHTER, Stephen.T.]

[BENCSIK JOSEF, BLAKE JAMES, KALLAN NICHOLAS, MITCHELL IAN, SPENCER KEITH, XIAO DENGMING, XU RUI, CHABOT CHRISTINE, LIANG JUN, SAFINA BRIAN] US;US The present invention provides compounds of Formula I , including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

[BENCSIK JOSEF R, BLAKE JAMES F, KALLAN NICHOLAS C, MITCHELL IAN S, SPENCER KEITH L, XIAO DENGMING, XU RUI, CHABOT CHRISTINE, LIANG JUN, SAFINA BRIAN S] US;US

[XIAO DENGMING, MITCHELL IAN S, BLAKE JAMES F, SAFINA BRIAN, LIANG JUN, SCHLACHTER STEPHEN T, XU RUI, KALLAN NICHOLAS C, SPENCER KEITH LEE, BENCSIK JOSEF R, LI JUN, CHABOT CHRISTINE, WALLACE ELI M, BANKA ANNA L] US

[MITCHELL IAN S, BLAKE JAMES F, KALLAN NICHOLAS C, XU RUI, XIAO DENGMING, SPENCER KEITH LEE, BENCSIK JOSEF R, LIANG JUN, SAFINA BRIAN, WALLACE ELI M, BANKA ANNA L, SCHLACHTER STEPHEN T, CHABOT CHRISTINE, LI JUN] US;US

[BENCSIK JOSEF R, BLAKE JAMES F, KALLAN NICHOLAS C, MITCHELL IAN S, SPENCER KEITH LEE, XIAO DENGMING, XU RUI, CHABOT CHRISTINE, DO STEVEN, LIANG JUN, SAFINA BRIAN, ZHANG BIRONG] US;US

[BENCSIK, Josef, BLAKE, James, F., KALLAN, Nicholas, C., MITCHELL, Ian, S., SPENCER, Keith, L., XIAO, Dengming, XU, Rui, CHABOT, Christine, DO, Steven, LIANG, Jun, SAFINA, Brian, ZHANG, Birong] 3200 Walnut Street Boulder, Colorado 80301;1 DNA Way South San Francisco, California 94080-4990;3200 Walnut Street Boulder, Colorado 80301;3200 Walnut Street Boulder, Colorado 80301;3200 Walnut Street Boulder, Colorado 80301;3200 Walnut Street Boulder, Colorado 80301;3200 Walnut Street Boulder, Colorado 80301;3200 Walnut Street Boulder, Colorado 80301;3200 Walnut Street Boulder, Colorado 80301;1 DNA Way South San Francisco, California 94080-4490;1 DNA Way South San Francisco, California 94080-4490;1 DNA Way South San Francisco, California 94080-4490;1 DNA Way South San Francisco, California 94080-4490;1 DNA Way South San Franciso, California 94080-4490 The present invention provides a compound and pharmaceutically acceptable salts thereof, comprising the Formula I. Also provided are methods of using the compound of this invention as an AKT protein kinase inhibitor and for the treatment of hyperproliferative diseases such as cancer.

[MITCHELL IAN S, BLAKE JAMES F, XU RUI, KALLAN NICHOLAS C, XIAO DENG-MING, SPENCER KEITH LEE, BENCSIK JOSEF R, WALLACE ELI M, SCHLACHTER STEPHEN T, BANKA ANNA L, LIANG JUN, SAFINA BRIAN, CHABOT CHRISTINE, ZHANG BIRONG, DO STEVE] US;US The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I: Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

[MITCHELL INA S, BLAKE JAMES F, XU RUI, KALLAN NICHOLAS C, XIAO DENGMING, SPENCER KEITH LEE, BENCSIK JOSEF R, LIANG JUN, SAFINA BRIAN, ZHANG BIRONG, CHABOT CHRISTINE, DO STEVEN, WALLACE ELI M, BANKA ANNA L, SCHLACHTER STEPHEN T] US;US