[SONG, Gengshen 宋更申, ZHANG, Honglei 张宏雷, CHEN, Xichao 陈玺朝, WANG, Huanyu 王环宇, HUANG, Dawei 黄大卫, YU, Xiaowen 余晓文, LIU, Yangjian 刘洋健, LI, Yuqing 李雨晴, YAN, Rucan 闫如灿, QIAO, Lianyong 乔连勇, LI, Xiaojuan 李晓娟, CHEN, Xiaoling 陈晓玲, SUN, Zhenlong 孙振龙, WANG, Shuai 王帅, DONG, Kai 董开, ZHANG, Jinyu 张晋瑜] Room 101, 1st Floor, Building 3, Yard 11, Kechuang 7th Street, Beijing Economic and Technological Development Zone 中国北京市大兴区北京经济技术开发区科创七街11号院3号楼1层101室, Beijing 100176Daxing, Beijing 100176 The present disclosure provides a compound of formula (I) or an N-oxide thereof, a solvate thereof, a pharmaceutically acceptable salt thereof, or a stereoisomer thereof, which is an extrahepatic targeted high-efficiency and low-toxicity cationic lipid compound. Further provided are compositions comprising the described compound and use thereof for the delivery of therapeutic or prophylactic agents.

[XU, Yanwei 许延伟, ZHANG, Wei 章威, LI, Yuqing 李雨晴, MING, Zhenyu 明振宇] Huawei Administration Building, Bantian, Longgang 中国广东省深圳市龙岗区坂田华为总部办公楼, Guangdong 518129Shenzhen, Guangdong 518129 Embodiments of the present application provide a clock synchronization method and a related device. The method comprises: determining time delay information and a measured clock offset of an n-th link among N links between at least two hosts to be synchronized, wherein n=1 ..., N, and N is a positive integer greater than or equal to 1; determining the weight of the n-th link according to the time delay information of the n-th link; and synchronizing clock time of said at least two hosts according to weights and measured clock offsets of the N links. Time delay information of the links is generally not completely the same, and therefore, determined weights of the links are not completely the same, either. According to the method, the clock time of said at least two hosts can be synchronized according to weight and measured clock offset of each link among the N links, so that errors are allocated to the links at different weights, thereby improving the clock synchronization accuracy of a plurality of hosts to be synchronized, and reducing a clock synchronization error.

[JIA, Xinghua 贾兴华, QI, Wangdong 齐望东, YOU, Xiaohu 尤肖虎, LIU, Peng 刘鹏, HUANG, Yongming 黄永明, LIU, Shengheng 刘升恒, LI, Yuqing 李雨晴] No. 9 中国江苏省南京市江宁区江宁经济开发区秣周东路9号, Jiangsu 211111Mozhou East Rd., Jiangning Economic and Technological Development Zone Jiangning DistrictNanjing, Jiangsu 211111 The present disclosure provides a non-line-of-sight propagation channel identification method and device, a wireless communication system and a medium. The method comprises: obtaining measured channel data corresponding to a wireless communication channel; preprocessing the measured channel data to determine first measured data, wherein the preprocessing comprises at least one of channel calibration, outlier removal and denoising; performing feature space transformation on the first measured data to determine second measured data; and inputting the second actual measurement data into a deep neural network (DNN), and determining a channel identification result output by the deep neural network (DNN). The method can address defects that an identification result corresponding to the channel data cannot be accurately obtained due to limitations of classic methods, and realizes a non-line-of-sight propagation channel identification method based on a deep neural network (DNN). The identification process of the measured channel data is simplified, and the channel identification result corresponding to the measured channel data can be accurately determined while the identification efficiency is improved.

[LI, Yuqing 李雨晴, LIU, Peng 刘鹏, QI, Wangdong 齐望东, YOU, Xiaohu 尤肖虎, HUANG, Yongming 黄永明, LIU, Shengheng 刘升恒, JIA, Xinghua 贾兴华] No. 9 中国江苏省南京市江宁区江宁经济开发区秣周东路9号, Jiangsu 211111Mozhou East Rd., Jiangning Economic and Technological Development Zone Jiangning DistrictNanjing, Jiangsu 211111 The present disclosure belongs to the technical field of wireless communication signal positioning. Disclosed are a data pre-processing method, apparatus and system in a wireless positioning system, and a medium. The method in the embodiments of the present disclosure comprises: a signal receiving end determining first channel state information (CSI) to be pre-processed; the signal receiving end estimating a sampling time deviation by means of compensating each sub-carrier of each antenna channel with a corresponding phase difference, and performing phase compensation on the first CSI by using the sampling time deviation, so as to obtain second CSI; the signal receiving end performing inverse fast Fourier transform on the second CSI, so as to obtain a channel impulse response (CIR) signal; the signal receiving end performing a right cyclic shift of a first amplitude sequence of the CIR signal by a first number of sampling points, wherein the first number is the number of sampling points in a rise time of a main path of the amplitude sequence of the CIR signal; and the signal receiving end performing amplitude normalization on the first amplitude sequence of the CIR signal, which has been subjected to the right cyclic shift, so as to obtain a second amplitude sequence of the CIR signal. The present disclosure belongs to the technical field of wireless communication signal positioning. Disclosed are a data pre-processing method, apparatus and system in a wireless positioning system, and a medium. The method in the embodiments of the present disclosure comprises: a signal receiving end determining first channel state information (CSI) to be pre-processed; the signal receiving end estimating a sampling time deviation by means of compensating each sub-carrier of each antenna channel with a corresponding phase difference, and performing phase compensation on the first CSI by using the sampling time deviation, so as to obtain second CSI; the signal receiving end performing inverse fast Fourier transform on the second CSI, so as to obtain a channel impulse response (CIR) signal; the signal receiving end performing a right cyclic shift of a first amplitude sequence of the CIR signal by a first number of sampling points, wherein the first number is the number of sampling points in a rise time of a main path of the amplitude sequence of the CIR signal; and the signal receiving end performing amplitude normalization on the first amplitude sequence of the CIR signal, which has been subjected to the right cyclic shift, so as to obtain a second amplitude sequence of the CIR signal.

[LI, Yuqing 李雨晴, LIU, Peng 刘鹏, QI, Wangdong 齐望东, YOU, Xiaohu 尤肖虎, HUANG, Yongming 黄永明, LIU, Shengheng 刘升恒] {No. 9 Mozhou East Rd., Jiangning Economic And Technological Development Zone, Jiangning District 中国江苏省南京市江宁区江宁经济开发区秣周东路9号, Jiangsu 211111Nanjing, Jiangsu 211111;CN CN(CN)(CN)} The present application relates to an information processing method and apparatus, a signal positioning method and apparatus, a device and a medium. The information processing method comprises: first performing time domain transformation on a plurality of pieces of channel state information of a target channel to correspondingly obtain a plurality of pieces of initial channel pulse response information; then normalizing influence parameters of each piece of initial channel pulse response information; and finally performing denoising processing on each piece of normalized initial channel pulse response information to obtain a plurality of pieces of target channel pulse response information, wherein the influence parameters represent parameters affecting the stability of the channel state information.