[BINTI WAN ABDUL HALIM, Wan Haslina, BINTI MOHD KHIALDIN, Safinaz, NG, Min Hwei, BINTI CHE MAN, Rohaina, MOHD ZAHIDIN, Aida Zairani] UKM 43600 BANGISELANGOR The present invention relates to tissue engineering, more particularly to a corneal-healing device capable of regenerating limbal stem cells of mammals upon temporarily implanting on a defected cornea comprising: a siloxane-hydrogel substrate which takes the form of a contact lens configured with confluent limbal stem cells and extracellular matrix components thereon. Further, there is provided a method for producing an autologous corneal-healing device capable of regenerating limbal stem cells of a mammals upon temporarily implanting on a defected cornea, the method comprising the steps of: preparing a siloxane-hydrogel substrate which takes the form of a contact lens; explanting limbal tissue of the mammals onto the substrate and incubating thereof; and culturing limbal stem cells obtained from the limbal tissue on the substrate in the presence of extracellular matrix components and growth medium until confluence, wherein the culturing step is conducted using air-lifting technique such that the stem cells substantially adhere to the substrate. The present invention relates to tissue engineering, more particularly to a corneal-healing device capable of regenerating limbal stem cells of mammals upon temporarily implanting on a defected cornea comprising: a siloxane-hydrogel substrate which takes the form of a contact lens configured with confluent limbal stem cells and extracellular matrix components thereon. Further, there is provided a method for producing an autologous corneal-healing device capable of regenerating lim

[WAN HASLINA BINTI WAN ABDUL HALIM, AIDA ZAIRANI BINTI MOHD ZAHIDIN, MOHD HAIRUL NIZAM BIN HARUN, KALAIVANI A/P CHELLAPPAN, AHMAD SOFFIAN BIN ZAHARI, CHENG TECK CHEE, THINAL RAJ, NORSHAMSIAH BINTI MD DIN] MY The present invention relates to an eye model (100) for an ophthalmologic surgery simulation. The eye model (100) of the present invention comprises a base (102) having a flat surface; a pair of eyeballs (104) with detachable sections; a pair of ocular motion devices (106) whereby the eyeball is affixed on the ocular motion device to imitate the actual eye movements of human eyes; and a face mask (108) mounted on top of the base (102) having a pair of eye holes (108a), a nose (108b), a forehead (108c) and cheeks (108e) to simulate a human face. The detachable sections of the eyeball includes an artificial transparent dome- shaped cornea (104a) affixed on top edge of an upper sclera capsule (104b); a lower sclera capsule (104c) affixed to bottom edge of the upper sclera capsule provided the transparent dome-shaped cornea (104a) and the lower sclera capsule (104c) are affixed to the upper sclera capsule by means of an annular snap fit mating (104d) and a circular snap fit mating (104d) respectively. The eyeball further comprises an artificial lens (104e) fitted in between the artificial cornea (104a) and upper sclera capsule (104b).