[PAN, Weidong 潘卫东, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, LIU, Yazhou 刘亚洲, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, LIU, Yazhou 刘亚洲, WANG, Ning 王宁, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, LIU, Yazhou 刘亚洲, WANG, Ning 王宁, HUANG, Lan 黄兰, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, LIU, Yazhou 刘亚洲, WANG, Ning 王宁, HUANG, Lan 黄兰, LIANG, Guangyi 梁光义, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, LIU, Yazhou 刘亚洲, WANG, Ning 王宁, HUANG, Lan 黄兰, LIANG, Guangyi 梁光义, ZHANG, Maosheng 张茂生, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, LIU, Yazhou 刘亚洲, WANG, Ning 王宁, HUANG, Lan 黄兰, LIANG, Guangyi 梁光义, ZHANG, Maosheng 张茂生, LI, Tianlei 李天磊, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, LIU, Yazhou 刘亚洲, WANG, Ning 王宁, HUANG, Lan 黄兰, LIANG, Guangyi 梁光义, ZHANG, Maosheng 张茂生, LI, Tianlei 李天磊, LOU, Huayong 娄华勇, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, LIU, Yazhou 刘亚洲, WANG, Ning 王宁, HUANG, Lan 黄兰, LIANG, Guangyi 梁光义, ZHANG, Maosheng 张茂生, LI, Tianlei 李天磊, LOU, Huayong 娄华勇, HU, Zhanxing 胡占兴, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, LIU, Yazhou 刘亚洲, WANG, Ning 王宁, HUANG, Lan 黄兰, LIANG, Guangyi 梁光义, ZHANG, Maosheng 张茂生, LI, Tianlei 李天磊, LOU, Huayong 娄华勇, HU, Zhanxing 胡占兴, LIU, Sheng 刘晟, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, LIU, Yazhou 刘亚洲, WANG, Ning 王宁, HUANG, Lan 黄兰, LIANG, Guangyi 梁光义, ZHANG, Maosheng 张茂生, LI, Tianlei 李天磊, LOU, Huayong 娄华勇, HU, Zhanxing 胡占兴, LIU, Sheng 刘晟, CAO, Peixue 曹佩雪, PAN, Weidong 潘卫东, FENG, Yibin 冯奕斌, LIU, Yazhou 刘亚洲, WANG, Ning 王宁, HUANG, Lan 黄兰, LIANG, Guangyi 梁光义, ZHANG, Maosheng 张茂生, LI, Tianlei 李天磊, LOU, Huayong 娄华勇, HU, Zhanxing 胡占兴, LIU, Sheng 刘晟, CAO, Peixue 曹佩雪, RUAN, Jinghua 阮婧华] 202 Shachong South Road, Nanming District 中国贵州省贵阳市南明区沙冲南路202号, Guizhou 550002Guiyang, Guizhou 550002;Versitech Limited Room 405A, Cyberport 4, 100 Cyberport Road 中国香港特别行政区数码港道100号数码港四座405A室, Hong KongHong Kong Disclosed are a compound of general formula (I), a single stereoisomer thereof, a mixture of stereoisomers thereof, and a prodrug, pharmaceutically acceptable salt and metabolite thereof, X1, X2, X3, X4, R1, R2, x, y and z being as defined in the present invention.

[CHEN, Chung-Chu 陈仲竹, CHEN, Chung-Chu 陈仲竹, HUANG, Chen-Ning 黄振宁, CHEN, Chung-Chu 陈仲竹, HUANG, Chen-Ning 黄振宁, YU, Tung-Ming 余东铭, CHEN, Chung-Chu 陈仲竹, HUANG, Chen-Ning 黄振宁, YU, Tung-Ming 余东铭, CHEN, Yin-Ruei 陈殷瑞, CHEN, Chung-Chu 陈仲竹, HUANG, Chen-Ning 黄振宁, YU, Tung-Ming 余东铭, CHEN, Yin-Ruei 陈殷瑞, YOU, Ming-Jian 游明谏, CHEN, Chung-Chu 陈仲竹, HUANG, Chen-Ning 黄振宁, YU, Tung-Ming 余东铭, CHEN, Yin-Ruei 陈殷瑞, YOU, Ming-Jian 游明谏, HUANG, Wen-Yen 黄文彦] 5F, Building D, No.22, Sec.2, Sheng Yi Rd. 中国台湾省新竹县竹北市生医路二段22号D栋5楼, Taiwan 30261Zhubei, Hsinchu, Taiwan 30261 A saliva treatment system (1, 5, 6) of an oral interface appliance (100, 200, 202, 500, 600, 600a, 600b) and a method for measuring liquid capacity in a reservoir (14, 55, 64) of the saliva treatment system (1, 5, 6). The saliva treatment system (1, 5, 6) comprises an oral interface appliance (100, 200, 202, 500, 600, 600a, 600b), a fluid adjuster (50) and a communicating tube (12, 52, 62). The oral interface appliance (100, 200, 202, 500, 600, 600a, 600b) is placed within the oral cavity of a user, the fluid adjuster (50) is communicated with the oral interface appliance (100, 200, 202, 500, 600, 600a, 600b) and the communicating tube (12, 52, 62). The communicating tube (12, 52, 62) is communicated with a negative pressure source (15, 56, 65) to create a negative pressure path between the oral interface appliance (100, 200, 202, 500, 600, 600a, 600b) and the negative pressure source (15, 56, 65), and saliva in the oral cavity of the user is collected into the reservoir (14, 55, 64) through the negative pressure path. The fluid adjuster (50) serves to restrict all fluids from flowing towards the communicating tube (12, 52, 62), so that air is fed, either constantly or as needed, into lines of the saliva treatment system (1, 5, 6) in the case that the negative pressure environment within the oral cavity of the user is maintained, contributing to removal of the saliva from the oral interface appliance (100, 200, 202, 500, 600, 600a, 600b) and the communicating tube (12, 52, 62). A saliva treatment system (1, 5, 6) of an oral interface appliance (100, 200, 202, 500, 600, 600a, 600b) and a method for measuring liquid capacity in a reservoir (14, 55, 64) of the saliva treatment system (1, 5, 6). The saliva treatment system (1, 5, 6) comprises an oral interface appliance (100, 200, 202, 500, 600, 600a, 600b), a fluid adjuster (50) and a communicating tube (12, 52, 62). The oral interface appliance (100, 200, 202, 500, 600, 600a, 600b) is placed within the oral cavity of a user, the fluid adjuster (50) is communicated with the oral interface appliance (100, 200, 202, 500, 600, 600a, 600b) and the communicating tube (12, 52, 62). The communicating tube (12, 52, 62) is communicated with a negative pressure source (15, 56, 65) to create a negative pressure path between the oral interface appliance (100, 200, 202, 500, 600, 600a, 600b) and the negative pressure source (15, 56, 65), and saliva in the oral cavity of the user is collected into the reservoir (14, 55, 64) through the negative pressure path. The fluid adjuster (50) serves to restrict all fluids from flowing towards the communicating tube (12, 52, 62), so that air is fed, either constantly or as needed, into lines of the saliva treatment system (1, 5, 6) in the case that the negative pressure environment within the oral cavity of the user is maintained, contributing to removal of the saliva from the oral interface appliance (100, 200, 202, 500, 600, 600a, 600b) and the communicating tube (12, 52, 62).

[GONG, Ming, GONG, Ming, DAI, Jin, GONG, Ming, DAI, Jin, CUI, Hao, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, LIN, Xingsen] 6F, HKUST SZ IER BLdg.No.9 Yuexing 1st Rd. Hi-Tech Park(South), Nanshan DistrictShenzhen, Guangdong 518057 Systems, methods, and devices are provided herein for recording operation history of movable objects. The recorded operation history may comprise outgoing operation commands sent from a remote controller of a remotely controlled vehicle, as well as incoming operation commands received by the remotely controlled vehicle. The recorded operation history may further comprise vehicle status data, such as data related to an operation process of the remotely controlled vehicle. The recorded operation history of a vehicle may be used to analyze a behavior of the vehicle.

[GONG, Ming, GONG, Ming, DAI, Jin, GONG, Ming, DAI, Jin, CUI, Hao, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, LIN, Xingsen] 6F, HKUST SZ IER Bldg.No.9 Yuexing 1st Rd. Hi-Tech Park(South), Nanshan DistrictShenzhen, Guangdong 518057 Systems and methods for UAV safety are provided. An authentication system may be used to confirm UAV and/or user identity and provide secured communications between users and UAVs. The UAVs may operate in accordance with a set of flight regulations. The set of flight regulations may be associated with a geo-fencing device in the vicinity of the UAV.

[GONG, Ming, GONG, Ming, DAI, Jin, GONG, Ming, DAI, Jin, CUI, Hao, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, LIN, Xingsen] 6F, HKUST SZ Ier Bldg.No. 9 Yuexing 1st Rd. Hi-Tech Park(South)Nanshan District, Shenzhen, Guangdong 518057 Systems and methods for UAV safety are provided. An authentication system may be used to confirm UAV and/or user identity and provide secured communications between users and UAVs. The UAVs may operate in accordance with a set of flight regulations. The set of flight regulations may be associated with a geo-fencing device in the vicinity of the UAV.

[GONG, Ming, GONG, Ming, DAI, Jin, GONG, Ming, DAI, Jin, CUI, Hao, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, LIN, Xingsen] 6F, HKUST SZ IER Bldg.No.9 Yuexing 1st Rd. Hi-Tech Park (South), Nanshan DistrictShenzhen, Guangdong 518057 Systems and methods for UAV safety are provided. An authentication system may be used to confirm UAV and/or user identity and provide secured communications between users and UAVs. The UAVs may operate in accordance with a set of flight regulations. The set of flight regulations may be associated with a geo-fencing device in the vicinity of the UAV.

[GONG, Ming, GONG, Ming, DAI, Jin, GONG, Ming, DAI, Jin, CUI, Hao, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, LIN, Xingsen] 6F, HKUST SZ IER BLdg.No.9 Yuexing 1st Rd. Hi-Tech Park(South), Nanshan DistrictShenzhen, Guangdong 518057 Systems and methods for UAV safety are provided. An authentication system may be used to confirm UAV and/or user identity and provide secured communications between users and UAVs. The UAVs may operate in accordance with a set of flight regulations. The set of flight regulations may be associated with a geo-fencing device in the vicinity of the UAV.

[GONG, Ming, GONG, Ming, DAI, Jin, GONG, Ming, DAI, Jin, CUI, Hao, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, LIN, Xingsen] 6F, HKUST SZ IER BLdg.No.9 Yuexing 1st Rd. Hi-Tech Park(South), Nanshan DistrictShenzhen, Guangdong 518057 Systems and methods for UAV safety are provided. An authentication system may be used to confirm UAV and/or user identity and provide secured communications between users and UAVs. The UAVs may operate in accordance with a set of flight regulations. The set of flight regulations may be associated with a geo-fencing device in the vicinity of the UAV.

[GONG, Ming, GONG, Ming, DAI, Jin, GONG, Ming, DAI, Jin, CUI, Hao, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, LIN, Xingsen] 6F, HKUST SZ IER BLdg.No.9 Yuexing 1st Rd. Hi-Tech Park (South), Nanshan DistrictShenzhen, Guangdong 518057 Systems and methods for UAV safety are provided. An authentication system may be used to confirm UAV and/or user identity and provide secured communications between users and UAVs. The UAVs may operate in accordance with a set of flight regulations. The set of flight regulations may be associated with a geo-fencing device in the vicinity of the UAV.

[GONG, Ming, GONG, Ming, DAI, Jin, GONG, Ming, DAI, Jin, CUI, Hao, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, GONG, Ming, DAI, Jin, CUI, Hao, WANG, Xiaodong, HUANG, Han, WU, Jun, FAN, Wei, MA, Ning, RONG, Xinhua, LIN, Xingsen] 6F, HKUST SZ IER BLdg.No.9 Yuexing 1st Rd., Hi-Tech Park (South), Nanshan DistrictShenzhen, Guangdong 518057 Systems, methods, and devices are provided herein for recording operation history of movable objects. The recorded operation history may comprise outgoing operation commands(270) sent from a remote controller(200) of a remotely controlled vehicle(300), as well as incoming operation commands(370) received by the remotely controlled vehicle(300). The recorded operation history may further comprise vehicle status data(375), such as data related to an operation process of the remotely controlled vehicle(300). The recorded operation history of a vehicle may be used to analyze a behavior of the vehicle.