[MAOBO DU, SHUZHI LIU, DANDAN LIU, JIGANG WANG, CHONG QIU, JUNZHE ZHANG, LIWEI GU, SHUO SHEN, SHENGNAN SHEN] CN Disclosed is a preparation method and application of the novel artemisinin derivative and its 5 liposomes. The method comprises the following steps: firstly, synthesizing artemisinin derivative (TPP-SS—ATS) which is sensitive to glutathione (GSH) and has mitochondrial targeting function; then the novel artemisinin derivative liposomes (TPP-SS—ATS—LS) were prepared by film dispersion method. The novel artemisinin derivative liposomes (TPP-SS—ATS—LS) prepared by the invention can realize dual-target drug delivery to tumour tissues and tumour cell mitochondria, 10 and remarkably improve the anti-tumour efficacy of artemisinin drugs.

[MAOBO DU, SHUZHI LIU, DANDAN LIU, JIGANG WANG, CHONG QIU, JUNZHE ZHANG, LIWEI GU, SHUO SHEN, SHENGNAN SHEN] CN Disclosed is a preparation method and application of the novel artemisinin derivative and its liposomes. The method comprises the following steps: firstly, synthesizing artemisinin derivative (TPP-SS—ATS) which is sensitive to glutathione (GSH) and has mitochondrial targeting function; then the novel artemisinin derivative liposomes (TPP-SS—ATS—LS) were prepared by film dispersion method. The novel artemisinin derivative liposomes (TPP-SS—ATS—LS) prepared by the invention can realize dual-target drug delivery to tumour tissues and tumour cell mitochondria, and remarkably improve the anti-tumour efficacy of artemisinin drugs.

[WU, Jianping 吴建平, JIANG, Ruixiang 姜瑞祥, JIANG, Jianguo 姜建国, HAN, Yonggang 韩永刚, DU, Haifu 杜海福, HAN, Dafeng 韩大峰, SHEN, Shuzhi 申书志, WANG, Diangang 王殿刚, WANG, Wanquan 王万全, GUO, Yuqiang 郭玉强, HAN, Dahua 韩大华, LI, Shuyin 李书印, HAN, Jie 韩杰] Room 005A, Floor B1, Building 1, No.5 Yard, Nansan Street, Huoxian Town 中国北京市通州区漷县镇南三街5号院1号楼B1层005A室, Beijing 101102Tongzhou District, Beijing 101102 Provided is an apparatus for shifting, turning over and replacing beddings (700) for a disabled person (900), comprising a fixing mechanism (100) and a moving mechanism (200). A first fixing mechanism (110) and a second fixing mechanism (120) are respectively clamped by means of a first clamping device (201) and a second clamping device (202), and a lifter (210) can drive the first clamping device (201) and the second clamping device (202) to move, so that the first fixing mechanism (110), the second fixing mechanism (120), the beddings (700) and the disabled person (900) can leave a bed body (600), thereby facilitating replacement of the beddings (700). By means of the fixing mechanism (100) and the moving mechanism (200), the disabled person (900) can leave the bed body (600), thereby reducing the labor intensity of nursing personnel and improving the experience of the disabled person (900). Further provided is a method for shifting, turning over and replacing beddings (700) for a disabled person (900). Provided is an apparatus for shifting, turning over and replacing beddings (700) for a disabled person (900), comprising a fixing mechanism (100) and a moving mechanism (200). A first fixing mechanism (110) and a second fixing mechanism (120) are respectively clamped by means of a first clamping device (201) and a second clamping device (202), and a lifter (210) can drive the first clamping device (201) and the second clamping device (202) to move, so that the first fixing mechanism (110), the second fixing mechanism (120), the beddings (700) and the disabled person (900) can leave a bed body (600), thereby facilitating replacement of the beddings (700). By means of the fixing mechanism (100) and the moving mechanism (200), the disabled person (900) can leave the bed body (600), thereby reducing the labor intensity of nursing personnel and improving the experience of the disabled person (900). Further provided is a method for shifting, turning over and replacing beddings (700) for a disabled person (900).

[Jianping Wu, Ruixiang Jiang, Jianguo Jiang, Yonggang Han, Haifu Du, Dafeng Han, Shuzhi Shen, Diangang Wang, Wanquan Wang, Yuqiang Guo, Dahua Han, Shuyin LI, Jie Han] CN Beijing An auxiliary cleaning device for a disabled person, comprising a movable support (1), a leg lifting device (2), and a cleaning device (3). The distances between a cleaning mechanism (33) and a part to be cleaned of a user in a first direction, a second direction, and a third direction are automatically adjusted, such that the cleaning mechanism (33) is driven by a mechanical arm mechanism (32) to move to a designated position near said part, so as to perform an operation such as cleaning of said part.

[WU, Jianping 吴建平, JIANG, Ruixiang 姜瑞祥, JIANG, Jianguo 姜建国, HAN, Yonggang 韩永刚, DU, Haifu 杜海福, HAN, Dafeng 韩大峰, SHEN, Shuzhi 申书志, WANG, Diangang 王殿刚, WANG, Wanquan 王万全, GUO, Yuqiang 郭玉强, HAN, Dahua 韩大华, LI, Shuyin 李书印, HAN, Jie 韩杰] Room 005A, Floor B1, Building 1, No. 5 Yard, Nansan Street, Huoxian Town 中国北京市通州区漷县镇南三街5号院1号楼B1层005A室, Beijing 101102Tongzhou District, Beijing 101102 An auxiliary cleaning device for a disabled person, comprising a movable support (1), a leg lifting device (2), and a cleaning device (3). The distances between a cleaning mechanism (33) and a part to be cleaned of a user in a first direction, a second direction, and a third direction are automatically adjusted, such that the cleaning mechanism (33) is driven by a mechanical arm mechanism (32) to move to a designated position near said part, so as to perform an operation such as cleaning of said part. An auxiliary cleaning device for a disabled person, comprising a movable support (1), a leg lifting device (2), and a cleaning device (3). The distances between a cleaning mechanism (33) and a part to be cleaned of a user in a first direction, a second direction, and a third direction are automatically adjusted, such that the cleaning mechanism (33) is driven by a mechanical arm mechanism (32) to move to a designated position near said part, so as to perform an operation such as cleaning of said part.

[WU, Jianping 吴建平, JIANG, Ruixiang 姜瑞祥, JIANG, Jianguo 姜建国, HAN, Yonggang 韩永刚, DU, Haifu 杜海福, HAN, Dafeng 韩大峰, SHEN, Shuzhi 申书志, WANG, Diangang 王殿刚, WANG, Wanquan 王万全, GUO, Yuqiang 郭玉强, HAN, Dahua 韩大华, LI, Shuyin 李书印, HAN, Jie 韩杰] {Room 005A, Floor B1, Building 1, No.5 Yard, Nansan Street, Huoxian Town 中国北京市通州区漷县镇南三街5号院1号楼B1层005A室, Beijing 101102Tongzhou, Beijing 101102;CN CN(CN)(CN)} The present invention provides a portable nursing apparatus, and relates to the technical field of nursing devices. The portable nursing apparatus comprises a lifting frame (100) and a cleaning control mechanism (200). When the lifting frame (100) needs to execute a lifting task, a foldable column body (120) and a base (110) can be switched to be perpendicular to each other, such that the lifting frame (100) is opened, and the position of a disabled person can be changed by means of a pulley mechanism (130). When the lifting frame (100) does not execute the lifting task, the foldable column body (120) and the base (110) can be switched to be parallel to each other, such that the lifting frame (100) is integrally folded, and carrying and transportation are facilitated, and moreover, as the space occupied by the lifting frame is greatly reduced, the storage is easier, and thus the portable nursing apparatus can meet storage requirements of common families. The present invention provides a portable nursing apparatus, and relates to the technical field of nursing devices. The portable nursing apparatus comprises a lifting frame (100) and a cleaning control mechanism (200). When the lifting frame (100) needs to execute a lifting task, a foldable column body (120) and a base (110) can be switched to be perpendicular to each other, such that the lifting frame (100) is opened, and the position of a disabled person can be changed by means of a pulley mechanism (130). When the lifting frame (100) does not execute the lifting task, the foldable column body (120) and the base (110) can be switched to be parallel to each other, such that the lifting frame (100) is integrally folded, and carrying and transportation are facilitated, and moreover, as the space occupied by the lifting frame is greatly reduced, the storage is easier, and thus the portable nursing apparatus can meet storage requirements of common families.

[WU, Jianping 吴建平, JIANG, Ruixiang 姜瑞祥, JIANG, Jianguo 姜建国, HAN, Yonggang 韩永刚, DU, Haifu 杜海福, HAN, Dafeng 韩大峰, SHEN, Shuzhi 申书志, WANG, Diangang 王殿刚, WANG, Wanquan 王万全, GUO, Yuqiang 郭玉强, HAN, Dahua 韩大华, LI, Shuyin 李书印, HAN, Jie 韩杰] Room 005A, Floor B1, Building 1, No.5 Yard, Nansan Street, Huoxian Town 中国北京市通州区漷县镇南三街5号院1号楼B1层005A室, Beijing 101102Tongzhou District, Beijing 101102 An intelligent bathing apparatus, which relates to the technical field of sanitary ware, is used for assisting in completing a bath by means of an intelligent apparatus, and can replace a personal bath towel before or after a bath, thereby reducing the risk of cross infection. The intelligent bathing apparatus comprises a cleaning mechanism (100) and a movement mechanism (500), wherein the cleaning mechanism (100) comprises a rotatable cleaning massager (200), and the cleaning massager (200) is used for carrying out rotational friction on the body of a user so as to clean and/or massage the body of the user. The cleaning massager (200) comprises a supporting member (210) and a replaceable bath cloth (110) arranged on the supporting member (210), wherein the bath cloth (110) covers at least part of a surface of the supporting member (210). The bath cloth (110) on the supporting member (210) can be replaced before or after a bath, such that the specificity of bath products can be ensured, and each person avoids the transmission of skin diseases due to cross-infection during his/her bath, thereby better providing a comfortable bathing experience for people. An intelligent bathing apparatus, which relates to the technical field of sanitary ware, is used for assisting in completing a bath by means of an intelligent apparatus, and can replace a personal bath towel before or after a bath, thereby reducing the risk of cross infection. The intelligent bathing apparatus comprises a cleaning mechanism (100) and a movement mechanism (500), wherein the cleaning mechanism (100) comprises a rotatable cleaning massager (200), and the cleaning massager (200) is used for carrying out rotational friction on the body of a user so as to clean and/or massage the body of the user. The cleaning massager (200) comprises a supporting member (210) and a replaceable bath cloth (110) arranged on the supporting member (210), wherein the bath cloth (110) covers at least part of a surface of the supporting member (210). The bath cloth (110) on the supporting member (210) can be replaced before or after a bath, such that the specificity of bath products can be ensured, and each person avoids the transmission of skin diseases due to cross-infection during his/her bath, thereby better providing a comfortable bathing experience for people.

[WU, Jianping 吴建平, JIANG, Ruixiang 姜瑞祥, JIANG, Jianguo 姜建国, HAN, Yonggang 韩永刚, DU, Haifu 杜海福, HAN, Dafeng 韩大峰, SHEN, Shuzhi 申书志, WANG, Diangang 王殿刚, WANG, Wanquan 王万全, GUO, Yuqiang 郭玉强, HAN, Dahua 韩大华, LI, Shuyin 李书印, HAN, Jie 韩杰] {Room 005A, Floor B1, Building 1, No.5 Yard, Nansan Street, Huoxian Town 中国北京市通州区漷县镇南三街5号院1号楼B1层005A室, Beijing 101102Tongzhou District, Beijing 101102;CN CN(CN)(CN)} A nursing care apparatus, pertaining to the technical field of sanitary devices, and used for solving the problem of post-defecation cleaning for disabled people. The nursing apparatus comprises a moving frame (100), a cleaning unit (200), and a lifting unit (300). The body of a user can be moved to a desired position by means of the lifting unit (300), and the cleaning unit (200) is enabled to be in a working state, so that the cleaning unit can move from the interior of the moving frame (100) to the exterior thereof so as to automatically or semi-automatically perform a cleaning operation on the user at the position, thereby eliminating the need for manual cleaning by nursing personnel, and thus reducing the working intensity of the nursing personnel. A nursing care apparatus, pertaining to the technical field of sanitary devices, and used for solving the problem of post-defecation cleaning for disabled people. The nursing apparatus comprises a moving frame (100), a cleaning unit (200), and a lifting unit (300). The body of a user can be moved to a desired position by means of the lifting unit (300), and the cleaning unit (200) is enabled to be in a working state, so that the cleaning unit can move from the interior of the moving frame (100) to the exterior thereof so as to automatically or semi-automatically perform a cleaning operation on the user at the position, thereby eliminating the need for manual cleaning by nursing personnel, and thus reducing the working intensity of the nursing personnel.

[SHEN SHUO, GU LIWEI, WANG JIGANG, LIU SHUZHI, DU MAOBO, GUO QIUYAN, XIA FEI, LIU DANDAN, ZHANG JUNZHE] CN The invention discloses a preparation method and application of the novel artemisinin derivative and its liposomes. The method comprises the following steps: firstly, synthesizing artemisinin derivative (TPP-SS-ATS) which is sensitive to glutathione (GSH) and has mitochondrial targeting function; then the novel artemisinin derivative liposomes (TPP-SS-ATS-LS) were prepared by film dispersion method. The novel artemisinin derivative liposomes (TPP-SS-ATS-LS) prepared by the invention can realize dual-target drug delivery to tumor tissues and tumor cell mitochondria, and remarkably improve the anti-tumor efficacy of artemisinin drugs.

[WU JIANPING, JIANG RUIXIANG, JIANG JIANGUO, HAN YONGGANG, DU HAIFU, HAN DAFENG, SHEN SHUZHI, WANG DIANGANG, WANG WANQUAN, GUO YUQIANG, HAN DAHUA, LI SHUYIN, HAN JIE] CN