in:(ZHAO, Chunhua)
TARGETED UBIQUITINATION DEGRADATION BRD4 PROTEIN COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
EP20747854.6
[ZHAO, Chuanwu, JIANG, Chunhua, ZHANG, Yan, ZHANG, Xuejiao, YANG, Jinlu, KANG, Jieqiong, ZHAO, Peipei]
No. 226 Huanghe Street, High-Tech Development Zone
Shijiazhuang
Hebei 050035, CN
The present invention relates to a compound represented by formula (I) or a tautomer, optical isomer, deuterated substance, oxynitride, solvate, pharmaceutically acceptable salt or prodrug thereof, a preparation method for the compound, a pharmaceutical composition containing same and a use of the compound or the pharmaceutical composition in the preparation of a drug for the prevention and/or treatment of cancer, tumors, viral infections, depression, neurological disorders, trauma, age-related cataracts, organ transplant rejection or autoimmune diseases.
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HIGH AND LOW TEMPERATURE TEST DEVICE FOR POWER BATTERY OF NEW ENERGY VEHICLE
ZA202501491A
[KONG CHUNHUA, QU YINGKAI, JIN SHOULING, ZHAO ZIHAN, QU ZETONG, ZHAO WEI, GAO SHUAI]
CN
Disclosed in the present invention is a high and low temperature test device for a power battery of a new energy vehicle, which relates to the field of battery testing. The test device includes a test chamber, a placing plate, an air outlet and a flame sensor, where the placing plate and the flame sensor are fixedly connected to an inner cavity wall of the test chamber, the air outlet is provided at an inner side of the test chamber, an upper portion of the test chamber is provided with an alarm lamp, and an interior of the test chamber is provided with a fire shielding cover assembly.
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ATOMIZATION ASSEMBLY AND ATOMIZATION DEVICE
PCT/CN2023/070838
[HUANG, Ke 黄科, ZHAO, Boyang 赵波洋, ZHAO, Guanyun 赵贯云, WEI, Chunhua 魏春花, ZUO, Jiang 左江, NIE, Ge 聂革, WANG, Lingquan 王灵权]
{BLOCK 1, SHAPUYANGYONG INDUSTRY PARK, SONGGANG, BAO’AN DISTRICT 中国广东省深圳市宝安区松岗街道沙浦社区洋涌工业区二路1号A栋综合楼三201及整栋, Guangdong 518000Shenzhen, Guangdong 518000;CN CN(CN)(CN)}
An atomization assembly (100) and an atomization device, relating to the technical field of aerosol generating devices. The atomization assembly (100) comprises a housing structure (101) and a heating structure (102). The housing structure (101) is provided with a liquid storage tank (13), a vent channel (16), and an atomization channel (15). The liquid storage tank (13) is used for storing an aerosol substrate. Two ends of the atomization channel (15) are communicated with external air. One end of the vent channel (16) is communicated with the atomization channel (15), and the other end of the vent channel (16) can be communicated with the liquid storage tank (13) so as to release pressure of the liquid storage tank (13). The housing structure (101) is further provided with storage cavities (332, 333, 334) formed in the inner wall of the vent channel (16). The storage cavities (332, 333, 334) are used for storing a condensate formed by liquefying the aerosol. The heating structure (102) is arranged in the atomization channel (15). The heating structure (102) can heat the aerosol substrate permeating the liquid storage tank (13) to form aerosol. Because the storage cavities (332, 333, 334) are formed in the inner wall of the vent channel (16), the condensate formed by liquefying the aerosol in the vent channel can flow into the storage cavities (332, 333, 334) for collection, thereby preventing the condensate from blocking the vent channel, and not affecting the pressure release of the liquid storage tank (13) by means of the vent channel.
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HEATING ASSEMBLY AND ATOMIZER APPLYING SAME, AND AEROSOL-GENERATING DEVICE
PCT/CN2024/089668
[AN, Pengzhan 安鹏展, WANG, Lingquan 王灵权, XIAO, Xiaopeng 肖小朋, WEI, Chunhua 魏春花, DING, Mingnei 丁明内, MO, Meini 莫美妮, ZHAO, Guanyun 赵贯云, ZHAO, Boyang 赵波洋]
201 and The Whole Building, No. 1, Comprehensive Building 3, 2nd Road, Yangyong Industrial Zone, Shapu Community, Songgang Street, Bao'an District, 中国广东省深圳市宝安区松岗街道沙浦社区洋涌工业区二路1号A栋综合楼三201及整栋, Guangdong 518000Shenzhen, Guangdong 518000
The present application discloses a heating assembly and an atomizer applying same, and an aerosol-generating device. The heating assembly comprises a first electrode area, a second electrode area and a heating wire structure; the heating wire structure comprises a first arc section, a first linear section, a second arc section, a second linear section, a third arc section, a third linear section and a fourth arc section which are connected in sequence; the thickness of the heating wire structure ranges from 0.03 mm to 0.15 mm; and the length of the heating wire structure ranges from 5 mm to 20 mm.
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ATOMIZER AND ATOMIZATION DEVICE
PCT/CN2023/083811
[XIAO, Liwei 肖力伟, WANG, Lingquan 王灵权, NIE, Ge 聂革, ZUO, Jiang 左江, WEI, Chunhua 魏春花, WANG, Xiaobin 王小斌, ZHAO, Guanyun 赵贯云, ZHAO, Boyang 赵波洋]
{Room 201, Building A, No. 1 Qianwan 1st Road, Qianhai Shenzhen-Hong 中国广东省深圳市前海深港合作区前湾一路1号A栋201室(入驻深圳市前海商务秘书有限公司), Guangdong 518000Kong Cooperation Zone, Shenzhen (Settled in Shenzhen Qianhai Commercial Secretary Co., Ltd.)Shenzhen, Guangdong 518000;CN CN(CN)(CN)}
The present invention relates to the technical field of atomization devices. Disclosed are an atomizer and an atomization device. The atomizer comprises an atomization assembly, a shell assembly and an air supplementing assembly, wherein the shell assembly comprises an atomization bin; the atomization bin is provided with a liquid storage cavity for storing a liquid matrix; the atomization assembly atomizes the liquid matrix into an aerosol; an air pressure balance bin is in one-way communication with the outside and the liquid storage cavity, respectively; a heating body is arranged in the air pressure balance bin; and the heating body adjusts the air pressure in the air pressure balance bin so as to balance the air pressure in the liquid storage cavity. When the heating body generates heat, the air pressure in the balance bin is increased, air in the air pressure balance bin enters the liquid storage cavity unidirectionally under the driving force of a pressure difference, and the air pressure in the liquid storage cavity is compensated; and when the heating body does not generate heat, the air pressure in the air pressure balance bin is lowered, and external air enters the air pressure balance bin unidirectionally, so as to supplement the air pressure balance bin. By means of the arrangement, air is actively supplemented to the liquid storage cavity, thereby avoiding a blockage, achieving a sensitive and timely response, and preventing core burning of the atomizer and leakage of the liquid matrix. The present invention relates to the technical field of atomization devices. Disclosed are an atomizer and an atomization device. The atomizer comprises an atomization assembly, a shell assembly and an air supplementing assembly, wherein the shell assembly comprises an atomization bin; the atomization bin is provided with a liquid storage cavity for storing a liquid matrix; the atomization assembly atomizes the liquid matrix into an aerosol; an air pressure balance bin is in one-way communication with the outside and the liquid storage cavity, respectively; a heating body is arranged in the air pressure balance bin; and the heating body adjusts the air pressure in the air pressure balance bin so as to balance the air pressure in the liquid storage cavity. When the heating body generates heat, the air pressure in the balance bin is increased, air in the air pressure balance bin enters the liquid storage cavity unidirectionally under the driving force of a pressure difference, and the air pressure in the liquid storage cavity is compensated; and when the heating body does not generate heat, the air pressure in the air pressure balance bin is lowered, and external air enters the air pressure balance bin unidirectionally, so as to supplement the air pressure balance bin. By means of the arrangement, air is actively supplemented to the liquid storage cavity, thereby avoiding a blockage, achieving a sensitive and timely response, and preventing core burning of the atomizer and leakage of the liquid matrix.
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TERNARY MATERIAL COATED WITH THREE-DIMENSIONAL NETWORK STRUCTURE OF COUPLED CARBON NANOTUBE-GRAPHENE COMPOSITE AND MANUFACTURING METHOD THEREOF
PCT/CN2016/085323
[WANG, Wenge 王文阁, SONG, Chunhua 宋春华, WANG, Ying 王瑛, QIAO, Wencan 乔文灿, ZHAO, Chenglong 赵成龙, FENG, Tao 冯涛, ZHANG, Zhihui 张智辉, ZHAO, Yanli 赵艳丽]
No.199, Nanjing Road 中国山东省菏泽市开发区南京路199号, Shandong 274000Heze, Shandong 274000
The present invention relates to the technical field of battery materials, and in particular discloses a ternary material coated with a three-dimensional network structure of a coupled carbon nanotube-graphene composite and a manufacturing method thereof. The ternary material coated with the three-dimensional network structure of the coupled carbon nanotube-graphene composite is made from a nickel-cobalt-manganese ternary material, carbon nanotubes and graphene. The method comprises: using polyvinylpyrrolidone as a dispersant, and at the same time, connecting graphene and carbon nanotubes by using a silane coupling agent and via liquid-phase self-assembly to form a three-dimensional network structure thereof; and next uniformly dispersing the coupled carbon nanotube-graphene composite material and the nickel-cobalt-manganese ternary material via a physical method, then coating the surface of the nickel-cobalt-manganese ternary material, and placing in an inert atmosphere to sinter, so as to obtain a uniformly-coated product. The product of the present invention has a high specific discharge capacity, long cycle life and a simple manufacturing process facilitating mass production.
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CULTURE MEDIUM AND METHOD FOR IN VITRO CULTURING HUMAN ADULT PRIMARY MESENCHYMAL STEM CELLS ON A LARGE SCALE, PRIMARY MESENCHYMAL STEM CELLS OBTAINED BY THE METHOD, THE USES THEREOF
PCT/CN2007/070637
[ZHAO, Chunhua, HAN, Qin, LI, Jing, SUN, Zhao, HU, Jianli, ZHU, Yashu, LU, Shan, BIAN, Chunjing]
5 Dongdan San Tiao, Dong Cheng District Beijing 100005;5 Dongdan San Tiao, Dong Cheng District Beijing 100005;5 Dongdan San Tiao, Dong Cheng District Beijing 100005;5 Dongdan San Tiao, Dong Cheng District Beijing 100005;5 Dongdan San Tiao, Dong Cheng District Beijing 100005;5 Dongdan San Tiao, Dong Cheng District Beijing 100005;5 Dongdan San Tiao, Dong Cheng District Beijing 100005;5 Dongdan San Tiao, Dong Cheng District Beijing 100005;5 Dongdan San Tiao, Dong Cheng District Beijing 100005
A method for in vitro preparing human adult primary mesenchymal stem cells (pMSCs, which are positive for Flk1 marker and Nanog marker) derived from human adult tissues (marrow) on a large scale and the products obtained by the same are provided. Uses of the method and the products obtained by the same in inhibiting the proliferation of tumor cells are also provided. By modifying the key processes and parameters of the preparation of pMSCs, for example simplifying the process of magnetic cell sorting, using human serum culture medium instead of bovine serum culture medium, and using the culture condition at low concentration oxygen (2%), the aim of preparing pMSCs on a large scale is achieved. By using the property of expressing Nanog gene of pMSCs, the novel use of pMSCs in inhibiting the proliferation of tumor cells is invented.
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HEATING ASSEMBLY, ATOMIZER, AND AEROSOL GENERATING DEVICE
PCT/CN2024/089656
[AN, Pengzhan 安鹏展, WANG, Lingquan 王灵权, XIAO, Xiaopeng 肖小朋, WEI, Chunhua 魏春花, DING, Mingnei 丁明内, MO, Meini 莫美妮, ZHAO, Guanyun 赵贯云, ZHAO, Boyang 赵波洋]
201 and the Whole Building, No. 1, Comprehensive Building 3, 2nd Road, Yangyong Industrial Zone 中国广东省深圳市宝安区松岗街道沙浦社区洋涌工业区二路1号A栋综合楼三201及整栋, Guangdong 518000Shapu Community, Songgang Street, Bao'an District, Shenzhen, GuangdongShenzhen, Guangdong 518000
Disclosed in the present application are a heating assembly, an atomizer, and an aerosol generating device. The heating assembly is arranged on at least one surface of a porous substrate. The porous substrate is used for guiding an atomization matrix. The heating assembly comprises two electrode connecting portions and a heating member connected between the two electrode connecting portions. The electrode connecting portions are used for connecting electrodes. The two ends of the heating member have the same arc-shaped structure. The curvature radius of the arc-shaped structure is a variable value. The connecting position between an arc-shaped structure and an electrode connecting portion is arranged close to the center of the heating member.
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PIPELINE-TYPE PRE-WATER-SEPARATION SYSTEM FOR OILFIELD PRODUCED FLUID
PCT/CN2024/091157
[WANG, Xiujun 王秀军, ZHANG, Jian 张健, HUA, Zhao 华朝, DU, Hong 杜虹, JING, Bo 靖波, CHEN, Jiaqing 陈家庆, HOU, Shengzhen 侯胜珍, ZHAO, Chunhua 赵春花]
No. 2121 Haichuan Road 中国天津市滨海新区海川路2121号, Tianjin 300459Binhai New Area, Tianjin 300459;Floors 8-14, Building 1, Courtyard 6, Taiyanggong South Street 中国北京市朝阳区太阳宫南街6号院1号楼8-14层, Beijing 100028Chaoyang District, Beijing 100028
The present invention relates to a pipeline-type pre-water-separation system for oilfield produced fluid. The system comprises a tubular degasser, a tubular mixing and demulsification device and a low-pressure-loss tubular dynamic cyclone separator. A liquid phase outlet of the tubular degasser is connected to an inlet of the tubular mixing and demulsification device. A gas phase outlet of the tubular degasser is connected to an inlet of an associated gas treatment system. The tubular mixing and demulsification device consists of a strong-turbulence mixing section and a medium-turbulence demulsification and coalescence section. A first outlet of the tubular mixing and demulsification device is connected to an inlet of the low-pressure-loss tubular dynamic cyclone separator. An oil phase separated by the low-pressure-loss tubular dynamic cyclone separator is discharged into a crude oil treatment system, and a separated water phase is discharged into a module for deep treatment of produced water and reinjection of qualified water. The system involves a simple process, a low manufacturing cost and a small occupied area of equipment, can be used for pre-water-separation for land and offshore high-water-content oilfields, and can further be used for pretreatment of produced liquid of deep-sea oilfields. The present invention relates to a pipeline-type pre-water-separation system for oilfield produced fluid. The system comprises a tubular degasser, a tubular mixing and demulsification device and a low-pressure-loss tubular dynamic cyclone separator. A liquid phase outlet of the tubular degasser is connected to an inlet of the tubular mixing and demulsification device. A gas phase outlet of the tubular degasser is connected to an inlet of an associated gas treatment system. The tubular mixing and demulsification device consists of a strong-turbulence mixing section and a medium-turbulence demulsification and coalescence section. A first outlet of the tubular mixing and demulsification device is connected to an inlet of the low-pressure-loss tubular dynamic cyclone separator. An oil phase separated by the low-pressure-loss tubular dynamic cyclone separator is discharged into a crude oil treatment system, and a separated water phase is discharged into a module for deep treatment of produced water and reinjection of qualified water. The system involves a simple process, a low manufacturing cost and a small occupied area of equipment, can be used for pre-water-separation for land and offshore high-water-content oilfields, and can further be used for pretreatment of produced liquid of deep-sea oilfields.
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System and method for frequency modulation based on direct current controllable load
US18337835
[Chunhua Mu, Peihao Yang, Pengyue Wu, Ganghu Sun, Faguang Liang, Dongfeng Chang, Zaisong Yu, Feng Gao, Shuichao Kou, Qi Chai, Xiaohui Wang, Liang Zhao, Wei Wang, Shuting Liang, Xinyu Guo, Hao Guo, Lisong Zhang, Yunfei Yan, Lei Xue, Junbo Zhao, Ting He, Zhipeng Li, Huanhuan Gao, Jiewen Wang, Yulun Chen, Mengyao Sun, Benqian Dai, Yue Yin, Jinghua Li]
CN Shaanxi
The system for frequency modulation based on Direct Current (DC) controllable load for a high-voltage plant includes a frequency modulator and a DC-controllable load for the high-voltage plant connected to the frequency modulator. The frequency modulator includes a centralized rectifier configured to adjust power of loads in the DC-controllable load in response to a frequency modulation command. The DC-controllable load is configured to respond to an adjustment of the power of loads performed by the centralized rectifier.
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