[HU, Shuting 胡舒婷, SIMON, James, E 西蒙J·E·, WU, Yizhen 吴忆箴, WANG, Mingfu 王明福, WU, Qingli 吴庆立] Unit 521, Biotech Center 2, Hong Kong Science Park, Shatin N.T. 中国香港特别行政区新界沙田香港科学园生物科技大楼2座521室, Hong KongHong Kong Disclosed is a use of Combretum Micranthum extract in cosmetics. Processes such as a solvent extraction method and a chromatographic method are specifically used, it is found that a Combretum Micranthum plant or its extract has the effects of moisturizing, anti-inflammatory, post-sun repair, repair of skin barrier, repair of UV-induced DNA damage, whitening, fading spots and resisting saccharification and the like. The prepared Combretum Micranthum extract can be added into cosmetics as an active ingredient thereof. The cosmetic or drug containing the Combretum Micranthum extract has the efficacies of moisturizing, anti-inflammatory, post-sun repair, repair of skin barrier, repair of UV-induced DNA damage, whitening, lightening spots and resisting saccharification and the like, thereby achieving the effect of skin care and beauty.