pa:(Jin-Wook Chung)
OILY PACLITAXEL COMPOSITION AND FORMULATION FOR CHEMOEMBOLIZATION AND PREPARATION METHOD THEREOF
PCT/KR2002/001722
[CHUNG, Hesson, JEONG, Seo, Young, KWON, Ick, Chan, PARK, Yeong, Taek, LEE, In, Hyun, PARK, Jae, Hyung, CHUNG, Jin, Wook, KIM, Young, Man]
39-1, Hawolgok-Dong, Sungbook-Ku 136-791 Seoul;1Ra-603, Shihwa-Industrial area, Jeungwang-Dong 429-450 Shiheung-Si, Kyunggi-Do;Ssangyong Apt. 3-507, GwanKyo-Dong, Nam-Ku 402-715 Incheon;Life Apt. 205-501, Munchonmaeul, Juyob 2-Dong, Ilsan-Ku 411-747 Koyang-Si, Kyunggi-Do;Siyoung Apt. 706-704, Hagye-Dong, Nowon-Ku 139-230 Seoul;Taeyoung Apt. 203-602, Bono 3-Dong 425-735 Ansan-Si, Kyunggi-Do;600-99, Shindaebang 1-Dong, Dongjak-Ku 156-011 Seoul;551-6, Banpo-Dong, Seocho-Ku 137-040 Seoul;Sampung Apt. 19-1101, Seocho 4-Dong, Seocho-Ku 137-779 Seoul;10/5, 302-203, Noryangjin 2-Dong, Dongjak-Ku 156-052 Seoul
Oily paclitaxel composition and formulation for chemoembolization and preparation method thereof solubilizing paclitaxel in an oily contrast medium. The composition of the present invention solubilizes paclitaxel and has an advantage of delivering anticancer drug to the target cells by chemoembolization since it is possible to visualize the blood vessel during the chemoembolization process. The present invention also relates to oily paclitaxel composition and formulation additionally comprising chemicals that prevent paclitaxel precipitation for prolonged preservation and the preparation method thereof. Since the composition of the present invention solubilize paclitaxel effectively and can be visualized during chemoembolization, it can be used for TACE to treat hepatoma and other solid tumors.
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PACLITAXEL MIXED COMPOSITION AND WATER-IN-OIL TYPE EMULSION FORMULATION FOR CHEMOEMBOLIZATION AND PREPARATION METHOD THEREOF
PCT/KR2001/001613
[CHUNG, Hesson, JEONG, Seo, Young, KWON, Ick, Chan, PARK, Jae, Hyung, CHUNG, Jin, Wook, KIM, Young, Man, LEE, In-Hyun]
39-1, Hawolgok-Dong, Sungbook-Ku 136-791 Seoul;1Ra-603, Shihwa-Industrial area, Jeungwang-Dong 429-450 Shiheung-Si, Kyunggi-Do;Ssangyong Apt. 3-507, Gwankyo-Dong, Nam-Ku 402-715 Incheon;Life Apt. 205-501, Munchonmaeul, Juyob 2-Dong, Ilsan-Ku 411-372 Koyang-Si, Kyunggi-Do;Siyoung Apt. 706-704, Hagye-Dong, Nowon-Ku 139-230 Seoul;551-6, Banpo-Dong, Seocho-Ku 137-040 Seoul;Sampung Apt. 19-1101, Seocho 3-Dong, Seocho-Ku 137-073 Seoul;10/5, 302-203, Noryangjin 2-Dong, Dongjak-Ku 156-052 Seoul;843-3, Singa-Dong, Kwangsan-Ku 506-307 Kwangju
The present invention relates to the paclitaxel mixed composition and water-in-oil type emulsion formulation for chemoembolization and preparation method thereof. The combinatory formulation of anticancer drugs can be easily prepared since the emulsion formulation of the present invention can include other hydrophilic or lipophilic drugs.
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COMPOSITION FOR SOLUBILIZATION OF PACLITAXEL AND PREPARATION METHOD THEREOF
PCT/KR2003/001427
[CHUNG, Hesson, JEONG, Seo-Young, KWON, Ick-Chan, PARK, Yeong-Taek, LEE, In-Hyun, YUK, Soon-Hong, CHOI, Young-Wook, PARK, Jae-Hyung, CHUNG, Jin-Wook]
39-1, Hawolgok-Dong, Sungbook-Gu Seoul 136-791;Ssangyong Apt. 3-507, Gwangyo-Dong, Nam-Gu Incheon 402-715;Munchonmaeul Life Apt. 205-501, Juyeop 2-Dong, Ilsan-Gu Goyang, Gyeonggi-Do 411-747;Siyoung Apt. 706-704, Hagye-Dong, Nowon-Gu Seoul 139-230;Taeyoung Apt. 203-602, Bono 3-Dong Ansan, Gyeonggi-Do 425-735;600-99, Sindaebang 1-Dong, Dongjak-Gu Seoul 156-011;Hanbit Apt. 133-1105, Oeun-Dong, Yuseong-Gu Daejeon 305-755;Jugong Apt. 76-501, Banpobon-Dong, Seocho-Gu Seoul 137-813;551-6, Banpo-Dong, Seocho-Gu Seoul 137-040;Sampung Apt. 19-1101, Seocho 4-Dong, Seocho-Gu Seoul 137-779
The present invention relates to a paclitaxel composition and the preparation methods thereof to solubilize paclitaxel wherein said composition comprises 4~90% by weight of at least one selected from the monoglycerides, 0.01~90% by weight of at least one oil and 0.01~20% by weight of paclitaxel. Also the present invention relates to a paclitaxel composition including emulsifiers and the preparation methods thereof to solubilize paclitaxel wherein said composition comprises 4~90% by weight of at least one selected from the monoglycerides, 0.01~90% by weight of at least one oil, 0.01~90% by weight of at least one emulsifier and 0.01~20% by weight of paclitaxel. The composition of the present invention is an effective paclitaxel delivery system since the composition solubilizes paclitaxel, does not form aggregates after being dispersed in water, adsorbs well on the intestinal wall, and therefore has high bioavailability.
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Oily paclitaxel composition and formulation for chemoembolization and preparation method thereof
US10489245
[Hesson Chung, Seo Young Jeong, Ick Chan Kwon, Yeong Taek Park, In Hyun Lee, Jae Hyung Park, Jin Wook Chung, Young man Kim]
RU Incheon
Oily paclitaxel composition and formulation for chemoembolization and preparation method thereof solubilizing paclitaxel in an oily contrast medium. The composition of the present invention solubilizes paclitaxel and has an advantage of delivering anticancer drug to the target cells by chemoembolization since it is possible to visualize the blood vessel during the chemoembolization process. The present invention also relates to oily paclitaxel composition and formulation additionally comprising chemicals that prevent paclitaxel precipitation for prolonged preservation and the preparation method thereof. Since the composition of the present invention solubilize paclitaxel effectively and can be visualized during chemoembolization, it can be used for TACE to treat hepatoma and other solid tumors.
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Composition for solubilization of paclitaxel and preparation method thereof
US10521669
[Hesson Chung, Seo-Young Jeong, Ick-Chan Kwon, Yeong-Taek Park, In-Hyun Lee, Soon-Hong Yuk, Young-Wook Choi, Jae-Hyung Park, Jin-Wook Chung]
KR Gwangyo-Dong
The present invention relates to a paclitaxel composition and the preparation methods thereof to solubilize paclitaxel wherein said composition comprises 4˜90% by weight of at least one selected from the monoglycerides, 0.01˜90% by weight of at least one oil and 0.01˜20% by weight of paclitaxel. Also the present invention relates to a paclitaxel composition including emulsifiers and the preparation methods thereof to solubilize paclitaxel wherein said composition comprises 4˜90% by weight of at least one selected from the monoglycerides, 0.01˜90% by weight of at least one oil, 0.01˜90% by weight of at least one emulsifier and 0.01˜20% by weight of paclitaxel. The composition of the present invention is an effective paclitaxel delivery system since the composition solubilizes paclitaxel, does not form aggregates after being dispersed in water, adsorbs well on the intestinal wall, and therefore has high bioavailability.
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OILY PACLITAXEL COMPOSITION AND FORMULATION FOR CHEMOEMBOLIZATION AND PREPARATION METHOD THEREOF
PCT/KR2001/001614
[CHUNG, Hesson, JEONG, Seo, Young, KWON, Ick, Chan, PARK, Jae, Hyung, CHUNG, Jin, Wook, KIM, Young, Man, LEE, In-Hyun]
39-1, Hawolgok-Dong Sungbook-Ku Seoul 136-791;1Ra-603, Shihwa-Industrial area Jeungwang-Dong Shiheung-Si Kyunggi-Do 429-450;Ssangyong Apt. 3-507 Gwankyo-Dong Nam-Ku Incheon 402-715;Life Apt. 205-501 Munchonmaeul Juyob 2-Dong Ilsan-Ku, Koyang-Si Kyunggi-Do 411-372;Siyoung Apt. 706-704 Hagye-Dong Nowon-Ku Seoul 139-230;551-6, Banpo-Dong Seocho-Ku Seoul 137-040;Sampung Apt. 19-1101 Seocho 3-Dong Seocho-Ku Seoul 137-073;10/5, 302-203, Noryangjin 2-Dong Dongjak-Ku Seoul 156-052;843-3, Singa-Dong Kwangsan-Ku Kwangju 506-307
Oily paclitaxel composition and formulation for chemoembolization and preparation method thereof solubilizing paclitaxel in an oily contrast medium. The composition of the present invention solubilizes paclitaxel and has an advantage of delivering anticancer drug to the target cells by chemoembolization since it is possible to visualize the blood vessel during the chemoembolization process.
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FACILITY MODULE FOR PRODUCTION AND STORAGE OF CELL THERAPY PRODUCT
PCT/KR2006/000955
[SUH, Dong-Sam, KO, Chang-Kwon, RYU, Seung-Ju, KOH, Sung-Jun, LEE, Eun-Young, JUNG, Soo-Jin, CHANG, Dong-Il, LEE, Jun-Keun, YOON, Hyun-Gi, CHANG, Hyang-Soon, YOO, Yong-Hyun, CHUNG, Jin-Wook, CHANG, Cheong-Ho]
10, 11th FL., Goodmorning-Shinhan Tower 23-2 Yoido-dong, Youngdeungpo-gu Seoul 150-712;139-221 103-403, Cheonggu 3-cha Apt., Junggye 1-dong, Nowon-gu Seoul 139-221;102-1203 Sungwon APT., Junggye 1(il)-dong, Nowon-gu Seoul 139-921;518-403, Jugong Apt., Haan-dong Gwangmyeong-si Gyeonggi-do 423-060;28-307, Samho Apt., Wolgye 3(sam)-dong, Nowon-gu Seoul 139-053;101 Sunhouse, 120-8 Huam-dong Yongsan-gu Seoul 140-190;201-407, Woosung Apt., 520-2 Jayang-dong, Gwangjin-gu Seoul 143-190;107-403, Dongbu Centreville Apt., 875-1 Banghwa-dong, Gangseo-gu Seoul 157-220;1-301, Noksibcho Golden Ville, 362 Wonjong-dong Ojeong-gu, Bucheon-si Gyeonggi-do 421-200;16-805, Jindalrae Apt., Yeoksam 2(i)-dong, Gangnam-gu Seoul 135-082;6-807, Shindong-a Apt., 344 Haengdang-dong, Seongdong-gu Seoul 133-070;109-403, Daelim Hansup Town Apt., 1 Susaek-dong, Eunpyeong-gu Seoul 122-090;101-706, Daelim Gyeongdong Apt., 1474 Gayang-dong, Gangseo-gu Seoul 157-200;503-802 Samhogarden., Banpo-dong, Seocho-gu Seoul 137-040
Provided is a facility module for production and storage of a cell therapy product. For this purpose, the facility module is comprised of a CT (Cell Therapy) -module 1 including a plurality of separately prefabricated units having individual-specific functions and having separately partitioned entrance and exit so as to minimize occurrence of contamination, and being capable of producing the cell therapy product, and a BC (Banking of Cell and Tissue)-module 2 including a plurality of separately prefabricated units having individual- specific functions and having separately partitioned entrance and exit so as to minimize occurrence of contamination, and being capable of storing hematopoietic stem cells and bone marrow cells and other cells for a prolonged period of time through appropriate processes.
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Method of forming polycrystalline silicon layer and atomic layer deposition apparatus used for the same
US13177936
[Yun-Mo Chung, Ki-Yong Lee, Min-Jae Jeong, Jin-Wook Seo, Jong-Won Hong, Heung-Yeol Na, Eu-Gene Kang, Seok-Rak Chang, Tae-Hoon Yang, Ji-Su Ahn, Young-Dae Kim, Byoung-Keon Park, Kil-Won Lee, Dong-Hyun Lee, Sang-Yon Yoon, Jong-Ryuk Park, Bo-Kyung Choi, Maxim Lisachenko]
KR Yongin
A method of forming a polycrystalline silicon layer and an atomic layer deposition apparatus used for the same. The method includes forming an amorphous silicon layer on a substrate, exposing the substrate having the amorphous silicon layer to a hydrophilic or hydrophobic gas atmosphere, placing a mask having at least one open and at least one closed portion over the amorphous silicon layer, irradiating UV light toward the amorphous silicon layer and the mask using a UV lamp, depositing a crystallization-inducing metal on the amorphous silicon layer, and annealing the substrate to crystallize the amorphous silicon layer into a polycrystalline silicon layer. This method and apparatus provide for controlling the seed position and grain size in the formation of a polycrystalline silicon layer.
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Display device and method of manufacturing the same
US13034818
[Byoung-Keon Park, Jin-Wook Seo, Ki-Yong Lee, Yun-Mo Chung, Jong-Ryuk Park, Tak-Young Lee, Dong-Hyun Lee, Kil-Won Lee, Byung-Soo So, Min-Jae Jeong, Yong-Duck Son, Seung-Kyu Park, Jae-Wan Jung]
KR Yongin
A display device including: a substrate; a first semiconductor layer disposed on the substrate; a second semiconductor layer disposed on the substrate and adjacent to the first semiconductor layer; a first insulation layer disposed on both the first semiconductor layer and the second semiconductor layer, the first insulation layer including a first opening forming a space between the first semiconductor layer and the second semiconductor layer; and a second insulation layer disposed on the first insulation layer and that fills the first opening.
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CELL MANIPULATION AND CULTIVATION EQUIPMENTS FOR THE PRODUCTION OF CELL THERAPY PRODUCTS
US12309868
[Jeong-Yong Choi, Dong-Sam Suh, Chang-Kwon Ko, Seung-Ju Ryu, Hyang-Soon Chang, Jin-Wook Chung, Cheong-Ho Chang]
KR Gyeonggi-do
Cell manipulation and cultivation equipment for the production of cell therapy products has developed for preventing contamination of cells and improving the utility of a space. The equipment includes a room for the production and testing of cell therapy products, the room having an inner space enclosed in all sides and an outer entrance/exit door provided at any one side thereof, an L-shaped partition installed in a position of the room for the production and testing of cell therapy products, the partition having an inner entrance/exit door provided at any one side thereof, and a clean bench device placed inside the partition, the clean bench device including first, second, and third clean benches for preventing contamination of cells and increasing the utility of a space to the maximum extent. The operating of the clean room and clean bench has advantages to prevent contamination and improving the quality and reliability of cell therapy products.
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