[WONG, Liang-Fong, MAZARAKIS, Nicholas, KINGSMAN, Susan, YIP, Ping, CORCORAN, Jonathan, McMAHON, Stephen, MADEN, Malcom] Medawar Centre Robert Robinson Avenue The Oxford Science Park Oxford OX4 4GA;Strand London WC2R 2LS;Oxford Biomedica (UK) Limited Medawar Centre Robert Robinson Avenue The Oxford Science Park Oxford OX4 4GA;Oxford Biomedica (UK) Limited Medawar Centre Robert Robinson Avenue The Oxford Science Park Oxford OX4 4GA;Oxford Biomedica (UK) Limited Medawar Centre Robert Robinson Avenue The Oxford Science Park Oxford OX4 4GA;Kings College London Strand London WC2R 2LS;Kings College London Strand London WC2R 2LS;Kings College London Strand London WC2R 2LS;Kings College London Strand London WC2R 2LS The present invention provides a system capable of delivering neuronal calcium sensor-1 (NCS-1), or a nucleotide sequence encoding NCS-1 to a target cell, for promoting neurite outgrowth. The system may be used in the manufacture of a pharmaceutical composition for the treatment of a condition such as spinal cord injury.

[PANZER, Scott, R., SPIRO, Peter, A., BANVILLE, Steven, C., SHAH, Purvi, CHALUP, Michael, S., CHANG, Simon, C., CHEN, Alice, D'SA, Steven, A., AMSHEY, Stefan, DAHL, Christopher, R., DAM, Tam, C., DANIELS, Susan, E., DUFOUR, Gerard, E., FLORES, Vincent, FONG, Willy, T., GREENAWALT, Lila, B., HILLMAN, Jennifer, L., JONES, Anissa, L., LIU, Tommy, F., ROSEBERRY, Ann, M., ROSEN, Bruce, H., RUSSO, Frank, D., STOCKDREHER, Theresa, K., DAFFO, Abel, WRIGHT, Rachel, J., YAP, Pierre, E., YU, Jimmy, Y., BRADLEY, Diana, L., BRATCHER, Shawn, R., CHEN, Wensheng, COHEN, Howard, J., HODGSON, David, M., LINCOLN, Stephen, E., JACKSON, Stuart] 3160 Porter Drive Palo Alto, CA 94304;571 Bobolink Circle Sunnyvale, CA 94087;410 Sheridan Avenue #333 Palo Alto, CA 94306;365 Monroe Drive Palo Alto, CA 94306;859 Salt Lake Drive San Jose, CA 95133;183 Acalanes Drive, Apt. #6 Sunnyvale, CA 94086;1901 Rock Street, #103 Mountain View, CA 94043;4405 Norwalk Drive, #22 San Jose, CA 95129;Apartment #13 40 Newell Road East Palo Alto, CA 94303;1605 20th Street San Francisco, CA 94107;41277 Roberts Avenue, #6 Fremont, CA 94538;2180 Mendota Way San Jose, CA;136 Seale Avenue Palo Alto, CA 94301;5327 Greenridge Road Castro Valley, CA 94552-2619;35000 Begonia Street Union City, CA 94587;572 Cambridge Street San Francisco, CA 94134;1596 Ballantree Way San Jose, CA 95118-2106;230 Monroe Drive, #17 Mountain View, CA 94040;445 South 15th Street San Jose, CA 95112;201 Ottilia Street Daly City, CA 94014;725 Sapphire Street Redwood City, CA 94061;177 Hanna Way Menlo Park, CA 94025;939 Rosette Court Sunnyvale, CA 94086;1596 Ontario Drive, #2 Sunnyvale, CA 94087;1750 Stokes Street, #70 San Jose, CA 95126;333 Anna Avenue Mountain View, CA 94043;201 Happy Hollow Court Lafayette, CA 94549-6243;3655 Wyndham Drive Fremont, CA 94536;3260 Crystal Heights Drive Soquel, CA 95073;550 Ortega Avenue, #B321 Mountain View, CA 94040;210 Easy Street #25 Mountain View, CA 94043;3272 Cowper Street Palo Alto, CA 94306-3004;2795 Windwood Drive, Apartment 165 Ann Arbor, MI 48105;725 Sapphire Street Redwood City, CA 94061;4913 Deep Creek Road Fremont, CA 94555 The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce anitbodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.

[William Andrews, David Chien, Qui-Lim Choo, Stephen Coates, Doris Coit, Charles Harrington, Susan Hilt, Michael Houghton, Angelica Medina-Selby, Sergio Pichuantes, Yiu-Lian Fong] US CA Oakland Recombinant production of immunogenic West Nile Virus (WNV) proteins is described. These proteins, heterodimers comprising the proteins, fusions thereof, polynucleotides encoding the proteins, and combinations thereof, as well as antibodies produced therefrom, can be used in immunogenic compositions for preventing, treating and diagnosing WNV infection. Also described are highly sensitive ELISA and strip immunoassay methods for detecting the presence of WNV in biological samples.

[PANZER, Scott, R., SPIRO, Peter, A., BANVILLE, Steven, C., SHAH, Purvi, CHALUP, Michael, S., CHANG, Simon, C., CHEN, Alice, D'SA, Steven, A., AMSHEY, Stefan, DAHL, Christopher, R., DAM, Tam, C., DANIELS, Susan, E., DUFOUR, Gerard, E., FLORES, Vincent, FONG, Willy, T., GREENAWALT, Lila, B., HILLMAN, Jennifer, L., JONES, Anissa, L., LIU, Tommy, F., ROSEBERRY, Ann, M., ROSEN, Bruce, H., RUSSO, Frank, D., STOCKDREHER, Theresa, K., DAFFO, Abel, WRIGHT, Rachel, J., YAP, Pierre, E., YU, Jimmy, Y., BRADLEY, Diana, L., BRATCHER, Shawn, R., CHEN, Wensheng, COHEN, Howard, J., HODGSON, David, M., LINCOLN, Stephen, E.] 3160 Porter Drive Palo Alto, CA 94304;571 Bobolink Circle Sunnyvale, CA 94087;410 Sheridan Avenue #333 Palo Alto, CA 94306;365 Monroe Drive Palo Alto, CA 94306;859 Salt Lake Drive San Jose, CA 95133;Apartment 6 183 Acalanes Drive Sunnyvale, CA 94086;1901 Rock Street #103 Mountain View, CA 94043;4405 Norwalk Drive #22 San Jose, CA 95129;Apartment #13 40 Newell Road East Palo Alto, CA 94303;1541 Canna Court Mountain View, CA 94043;41277 Roberts Avenue #6 Fremont, CA 94538;2180 Mendota Way San Jose, CA;136 Seale Avenue Palo Alto, CA 94301;5327 Greenridge Road Castro Valley, CA 94552-2619;35000 Begonia Street Union City, CA 94587;572 Cambridge Street San Francisco, CA 94134;1596 Ballantree Way San Jose, CA 95118-2106;230 Monrow Drive #12 Mountain View, CA 94040;445 South 15th Street San Jose, CA 95112;201 Ottilia Street Daly City, CA 94014;725 Sapphire Street Redwood City, CA 94061;177 Hanna Way Menlo Park, CA 94025;939 Rosette Court Sunnyvale, CA 94086;1596 Ontario Drive #2 Sunnyvale, CA 94087;1750 Stokes Street #70 San Jose, CA 95126;333 Anna Avenue Mountain View, CA 94043;201 Happy Hollow Court Lafayette, CA 94549-6243;3655 Wyndham Drive Fremont, CA 94536;3260 Crystal Heights Drive Soquel, CA 95073;550 Ortega Avenue #B321 Mountain View, CA 94040;210 Easy Street #25 Mountain View, CA 94043;3272 Cowper Street Palo Alto, CA 94306-3004;567 Addison Avenue Palo Alto, CA 94301;725 Sapphire Street Redwood City, CA 94061 The present invention provides purified secretory polynucleotides (sptm). Also encompassed are the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing sptm for the expression of SPTM. The invention additionally provides for the use of isolated and purified SPTM to induce antibodies and to screen libraries of compounds and the use of anti-SPTM antibodies in diagnostic assays. Also provided are microarrays containing sptm and methods of use.

[DEVLIN, James, J., DOYLE, Michael, FONG, Susan] 4560 Horton Street Emeryville, CA 94608;1146 Upper Happy Valley Road Lafayette, CA 94549;2709 Mountaingate Way Oakland, CA 94611;1931 Dwight Way, #20 Berkeley, CA 94704 Peptides and methods for identifying the same using a random peptide library are described wherein the peptides have the property of affecting cell adhesion or aggregation, including interfering with the aggregation of platelets.

[Cornelia Bellamacina, Abran Costales, Brandon Doughan, Susan Fong, Zhenhai Gao, Thomas Hendrickson, Barry Levine, Xiaodong Lin, Timothy Machajewski, Christopher McBride, William Antonios-McCrea, Maureen McKenna, Kris Mendenhall, Alice Rico, Cynthia Shafer, X. Wang, Yi Xia, Yasheen Zhou] US CA Castro Valley 2-Amino-quinazolin-5-one compounds, stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-quinazolin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the 2-amino-quinazolin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cell proliferative diseases.

[PANZER, Scott, R., SPIRO, Peter, A., BANVILLE, Steven, C., SHAH, Purvi, CHALUP, Michael, S., CHANG, Simon, C., CHEN, Alice, D'SA, Steven, A., AMSHEY, Stefan, DAHL, Christopher, R., DAM, Tam, C., DANIELS, Susan, E., DUFOUR, Gerard, E., FLORES, Vincent, FONG, Willy, T., GREENAWALT, Lila, B., HILLMAN, Jennifer, L., JONES, Anissa, L., LIU, Tommy, F., ROSEBERRY, Ann, M., ROSEN, Bruce, H., RUSSO, Frank, D., STOCKDREHER, Theresa, K., DAFFO, Abel, WRIGHT, Rachel, J., YAP, Pierre, E., YU, Jimmy, Y., BRADLEY, Diana, L., BRATCHER, Shawn, R., CHEN, Wensheng, COHEN, Howard, J., HODGSON, David, M., LINCOLN, Stephen, E., JACKSON, Stuart] 3160 Porter Drive Palo Alto, CA 94304;571 Bobolink Circle Sunnyvale, CA 94087;410 Sheridan Avenue #333 Palo Alto, CA 94306;365 Monroe Drive Palo Alto, CA 94306;859 Salt Lake Drive San Jose, CA 95133;183 Acalanes Drive, Apt.#6 Sunnyvale, CA 94086;1901 Rock Street #103 Mountain View, CA 94043;4405 Norwalk Drive #22 San Jose, CA 95129;40 Newell Road, Apt.#13 East Palo Alto, CA 94303;1605 20th Street San Francisco, CA 94107;41277 Roberts Avenue #6 Fremont, CA 94538;2180 Mendota Way San Jose, CA;136 Seale Avenue Palo Alto, CA 94301;5327 Greenridge Road Castro Valley, CA 94552-2619;35000 Begonia Street Union City, CA 94587;572 Cambridge Street San Francisco, CA 94134;1596 Ballantree Way San Jose, CA 95118-2106;230 Monroe Drive, #17 Mountain View, CA 94040;445 South 15th Street San Jose, CA 95112;201 Ottilia Street Daly City, CA 94014;725 Sapphire Street Redwood City, CA 94061;177 Hanna Way Menlo Park, CA 94025;939 Rosette Court Sunnyvale, CA 94086;1596 Ontario Drive #2 Sunnyvale, CA 94087;1750 Stokes Street #70 San Jose, CA 95126;333 Anna Avenue Mountain View, CA 94043;201 Happy Hollow Court Lafayette, CA 94549-6243;3655 Wyndham Drive Fremont, CA 94536;3260 Crystal Heights Drive Soquel, CA 95073;550 Ortega Avenue #B321 Mountain View, CA 94040;210 Easy Street #25 Mountain View, CA 94043;3272 Cowper Street Palo Alto, CA 94306-3004;2795 Windwood Drive, Apartment 165 Ann Arbor, MI 48105;725 Sapphire Street Redwood City, CA 94061;230 Monroe Drive, #17 Mountain View, CA 94040 The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing dithp for the expression of DITHP. The invention additionally provides for the use of isolated and purified DITHP to induce antibodies and to screen libraries of compounds and the use of anti-DITHP antibodies in diagnostic assays. Also provided are microarrays containing dithp and methods of use.

[Scott Panzer, Peter Shapiro, Steven Banville, Purvi Shah, Michael Chalup, Simon Chang, Alice Chen, Steven D'sa, Stefan Amshey, Christopher Dahl, Tam Dam, Susan Daniels, Gerard Dufour, Vincent Flores, Willy Fong, Lila Greenawalt, Jennifer Jackson, Anissa Jones, Tommy Liu, Ann Roseberry Lincoln, Bruce Rosen, Frank Russo, Theresa Stockdreher, Abel Daffo, Rachel Wright, Pierre Yap, Jimmy Yu, Diana Bradley, Shawn Bratcher, Wensheng Chen, Howard Cohen, David Hodgson, Stephen Lincoln, Stuart Jackson] US CA Sunnyvale The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce anitbodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.

[Scott R. Panzer, Peter A. Spiro, Steven C. Banville, Purvi Shah, Michael S. Chalup, Simon C. Chang, Alice Chen, Steven D'sa, Stefan Amshey, Christopher R. Dahl, Tam C. Dam, Susan E. Daniels, Gerard E. Dufour, Vincent Flores, Willy T. Fong, Lila B. Greenawalt, Jennifer L. Hillman, Anissa L. Jones, Tommy F. Liu, Ann M. Roseberry, Bruce H. Rosen, Frank D. Russo, Theresa K. Stockdreher, Abel Daffo, Rachel J. Wright, Pierre E. Yap, Jimmy Y. Yu, Diana L. Bradley, Shawn R. Bratcher, Wensheng Chen, Howard J. Cohen, David M. Hodgson, Stephen E. Lincoln] US CA Sunnyvale The present invention provides purified secretory polynucleotides (sptm). Also encompassed are the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing sptm for the expression of SPTM. The invention additionally provides for the use of isolated and purified SPTM to induce antibodies and to screen libraries of compounds and the use of anti-SPTM antibodies in diagnostic assays. Also provided are microarrays containing sptm and methods of use.

[TAI, Yu-Chong, NANDRA, Mandheerej S., EDGERTON, Victor Reggie, ROY, Roland R., GERASIMENKO, Yury, BURDICK, Joel W., HARKEMA, Susan J., ANGELI, Claudia A., RODGER, Damien Craig, FONG, Andy, LAVROV, Igor] 1200 East California Boulevard Pasadena, California 91125;1111 Franklin Street Oakland, California 94607;201 E. Jefferson Street, Suite 215 Louisville, Kentucky 40202;3191 East California Boulevard Pasadena, California 91107;746 Los Robles Avenue Pasadena, California 91106;2200 Linda Flora Drive Los Angeles, California 90077;5701 S. Kiyot Way #3 Playa Vista, California 90094;817 Levering Ave., Apt. 6 Los Angeles, California 90024;1035 E. Woodbury Rd. Pasadena, CA 91104;251 1 Woodside Road Louisville, Kentucky 40207;Ill04 Oak Bend Ct Louisville, Kentucky 40241;1748 Foothill St, Apt A South Pasadena, CA 91030;858 Moraga Drive #3 Los Angeles, CA 90049;6714 Los Verdes Drive, #3 Rancho Palos Verdes, CA 90275 An implantable electrode array assembly configured to apply electrical stimulation to the spinal cord. A substantially electrically nonconductive layer of the device has a first portion positionable alongside the spinal cord that includes a plurality of first openings. The layer has a second portion that includes a plurality of second openings. Electrodes and traces are positioned inside a peripheral portion of a body portion of the device and alongside the layer. At least one of the first openings is adjacent each of the electrodes to provide a pathway through which the electrode may provide electrical stimulation to the spinal cord. At least one of the second openings is adjacent each of the traces to provide a pathway through which the trace may receive electrical stimulation. At least one trace is connected to each electrode and configured to conduct electrical stimulation received by the trace(s) to the electrode