[CHEON, Jae Hee 천재희, NAM, Chung Mo 남정모, PARK, Ji Hye 박지혜, ZHANG, Hyun Soo 장현수, KIM, Joo Sung 김주성, KIM, Young Ho 김영호, PARK, Dong Il 박동일, YE, Byong Duk 예병덕, JEEN, Yoontae 진윤태, KIM, Se Hyun 김세현] 50, Yonsei-ro 03722 서울특별시 서대문구 연세로 50Seodaemun-guSeoul 03722;101 Daehak-ro 03080 서울특별시 종로구 대학로 101Jongno-guSeoul 03080;48 Itaewon-ro 55-gil 04348 서울특별시 용산구 이태원로55길 48Yongsan-guSeoul 04348;29 Saemunan-ro 03181 서울특별시 종로구 새문안로 29Jongno-guSeoul 03181;93 Daehak-ro 44610 울산광역시 남구 대학로 93Nam-guUlsan 44610;88 Olympic-ro 43-gil 05505 서울특별시 송파구 올림픽로43길 88Songpa-guSeoul 05505;145 Anam-ro 02841 서울특별시 성북구 안암로 145Seongbuk-guSeoul 02841;152 Jukjeon-ro 16890 경기도 용인시 수지구 죽전로 152Suji-gu, Yongin-siGyeonggi-do 16890 The present specification provides a method for providing information on ulcerative colitis by means of a processor, the method comprising: a step for receiving a Korean Ulcerative Colitis-Specific Questionnaire (K-UCSQ) score for an individual; and a step for determining an inflammatory bowel disease prognosis for the individual on the basis of the received K-UCSQ score. The present specification provides a method for providing information on ulcerative colitis by means of a processor, the method comprising: a step for receiving a Korean Ulcerative Colitis-Specific Questionnaire (K-UCSQ) score for an individual; and a step for determining an inflammatory bowel disease prognosis for the individual on the basis of the received K-UCSQ score.

[KIM, Sunghwan 김성환, PARK, Hosung 박호성, NO, Albert 노알버트, KIM, Jae Won 김재원, JEONG, Jaeho 정재호, NO, Jong Seon 노종선] 93, Daehak-ro, 44610 울산시 남구 대학로 93, UlsanNam-gu,Ulsan 44610;1, Gwanak-ro, 08826 서울시 관악구 관악로 1, SeoulGwanak-gu,Seoul 08826;1Fl., 77, Yongbong-ro, 61186 광주시 북구 용봉로 77, 1층, GwangjuBuk-gu,Gwangju 61186;94, Wausan-ro, 04066 서울시 마포구 와우산로 94, SeoulMapo-gu,Seoul 04066 A flexible information-based decoding method of a DNA storage device, a program and an apparatus are provided. A flexible information-based decoding method of a DNA storage device, according to one embodiment of the present invention, comprises the steps in which a computer: acquires a first sequence and a quality score of the first sequence; and calculates a base probability at each location in the first sequence on the basis of the quality score, wherein the quality score includes an error rate of each base included in the first sequence, and the base probability can be a probability corresponding to each of adenine (A), guanine (G), cytosine (C) and thymine (T) which are bases at specific locations of the first sequence.

[JEONG, Jaeho 정재호, PARK, Hosung 박호성, PARK, Seong Joon 박성준, NO, Jong Seon 노종선, KIM, Sunghwan 김성환, NO, Albert 노알버트] 1, Gwanak-ro, 08826 서울시 관악구 관악로 1, SeoulGwanak-gu,Seoul 08826;1Fl., 77, Yongbong-ro, 61186 광주시 북구 용봉로 77, 1층, GwangjuBuk-gu,Gwangju 61186;93, Daehak-ro, 44610 울산시 남구 대학로 93, UlsanNam-gu,Ulsan 44610;94, Wausan-ro, 04066 서울시 마포구 와우산로 94, SeoulMapo-gu,Seoul 04066 The present invention relates to a method, program, and apparatus for decoding based on sequence clustering of a DNA storage device. According to the present invention, when base sequences with certain lengths are extracted from nucleotide sequences formed through a stitch algorithm, clustering is conducted on the basis of the degree of identity, wherein nucleotide sequences with small errors as well as completely identical nucleotide sequences are contained within the cluster, whereby the error data can be used to improve decoding efficiency and reduce the final error rate.

[PARK, Seong Joon 박성준, JEONG, Jaeho 정재호, NO, Jong Seon 노종선, PARK, Hosung 박호성, KIM, Sunghwan 김성환, NO, Albert 노알버트] 1, Gwanak-ro, 08826 서울특별시 관악구 관악로 1, SeoulGwanak-gu,Seoul 08826;1Fl., 77, Yongbong-ro, 61186 광주광역시 북구 용봉로 77, 1층, GwangjuBuk-gu,Gwangju 61186;93, Daehak-ro, 44610 울산광역시 남구 대학로 93, UlsanNam-gu,Ulsan 44610;94, Wausan-ro, 04066 서울특별시 마포구 와우산로 94, SeoulMapo-gu,Seoul 04066 The present invention provides a DNA data encoding and decoding method using a low-density parity check code, a program, and a device. According to the present invention, by excluding base sequences having biochemical characteristics inducing three types of errors existing in a DNA storage device, and checking the ratio of G and C of finally generated base sequences and the number of continuous sequences, base sequences not satisfying a reference condition may be excluded. Therefore, when decoding data, possibility of error occurrences is lowered, and data can be restored with higher accuracy.

[LEE, Sunyong 이선영, AHN, Sung-Hoon 안성훈, CHU, Won-Shik 추원식, CHUN, Doo-Man 천두만, KIM, Hyungsub 김형섭, CHOI, Dahyun 최다현, KIM, Kwangmin 김광민] 55, Hanyangdaehak-ro 15588 경기도 안산시 상록구 한양대학로 55, Gyeonggi-doSangrok-gu Ansan-siGyeonggi-do 15588;1, Gwanak-ro 08826 서울시 관악구 관악로 1, SeoulGwanak-guSeoul 08826;93, Daehak-ro 44610 울산시 남구 대학로 93, UlsanNam-guUlsan 44610 Provided is an electrochromic element comprising an electrochromic layer and an ion storage layer. An electrochromic element, comprising an electrochromic layer and an ion storage layer, can comprise: a first substrate; a second substrate facing the first substrate; electrolyte provided between the first substrate and the second substrate; a first electrode provided between the first substrate and the electrolyte; an ion storage layer provided between the first electrode and the electrolyte and comprising nickel oxide and titanium oxide; a second electrode provided between the second substrate and the electrolyte; and an electrochromic layer provided between the second electrode and the electrolyte.

[CHUN, Doo-Man 천두만, NASIM, Mohammad Nur E Alam Al 나심모하마드 누르, LEE, Caroline Sunyong 이선영, AHN, Sung-Hoon 안성훈, CHU, Won-Shik 추원식] 93 Daehak-ro 44610 울산시 남구 대학로 93, UlsanNam-guUlsan 44610;55, Hanyangdaehak-ro, Sangnok-gu 15588 경기도 안산시 상록구 한양대학로 55, Gyeonggi-doAnsan-siGyeonggi-do 15588;1, Gwanak-ro 08826 서울시 관악구 관악로 1, SeoulGwanak-guSeoul 08826 The graphene flake thin film manufacturing apparatus according to the present invention, which produces graphene on a substrate by using graphite powder, comprises: a substrate disposition unit having a substrate disposed at one side thereof; a nozzle unit which is in a tubular shape having an interior space so as to allow for the movement of graphite powder, has a spray hole at one side thereof, and sprays the graphite powder onto the substrate through the spray hole; and a graphite supply unit communicating with the interior space of the nozzle unit and supplying the graphite powder to the interior space. The graphene flake thin film manufacturing apparatus and graphene flake thin film manufacturing method, according to the present invention, are configured such that graphene flake thin films can be manufactured by depositing graphene on substrates by spraying graphite powder via the nozzle unit so as for same to collide with the substrates at a high speed.

[HAN, Won Shik 한원식, LEE, Han Byoel 이한별, PARK, In Ae 박인애, RYU, Han Suk 유한석, AHN, Sei Hyun 안세현, LEE, Jong Won 이종원, LEE, Sae Byul 이새별, LEE, Hee Jin 이희진, KIM, Ae Ree 김애리, KIM, Chung Yeul 김정렬, YOON, Sung Roh 윤성로, KIM, Sun 김선, KWON, Sun Young 권선영, KIM, Min Su 김민수, JO, Jeong Hee 조정희] (Yeongeon-dong) 03080 서울시 종로구 대학로 101 (연건동), Seoul101, Daehak-ro,Jongno-gu,Seoul 03080;(Sinrim-dong) 08826 서울시 관악구 관악로 1 (신림동), Seoul1, Gwanak-ro,Gwanak-gu,Seoul 08826;(Anam-dong5ga) 02841 서울시 성북구 안암로 145, 고려대학교 (안암동5가), SeoulKoreauniversity, 145, Anam-ro,Seongbuk-gu,Seoul 02841;(Pungnap-dong) 05505 서울시 송파구 올림픽로 43길 88 (풍납동), Seoul88, Olympic-ro 43-gil,Songpa-gu,Seoul 05505;(Mugeo-dong) 44610 울산시 남구 대학로 93 (무거동), Ulsan93, Daehak-ro,Nam-gu,Ulsan 44610 A machine learning-based method for prediction of breast cancer prognosis using next-generation sequencing comprises the steps of: allowing a computer device to use RNA sequencing data of a subject tissue to measure an expression level of a target gene; allowing the computer device to input the expression level of the target gene into an artificial neural network adapted beforehand; and allowing the computer device to estimate the prognosis of breast cancer of the subject on the basis of the output value of the artificial neural network. The artificial neural network is adapted beforehand to have target gene expression levels of multiple samples as input values and to output results depending on oncotype DX recurrence scores for the multiple samples. A machine learning-based method for prediction of breast cancer prognosis using next-generation sequencing comprises the steps of: allowing a computer device to use RNA sequencing data of a subject tissue to measure an expression level of a target gene; allowing the computer device to input the expression level of the target gene into an artificial neural network adapted beforehand; and allowing the computer device to estimate the prognosis of breast cancer of the subject on the basis of the output value of the artificial neural network. The artificial neural network is adapted beforehand to have target gene expression levels of multiple samples as input values and to output results depending on oncotype DX recurrence scores for the multiple samples.

[KIM, Yang-Hee 김양희, KIM, Ki Ryeong 김기령, LIM, Dongyeol 임동렬, KIM, Hyung Wook 김형욱, KOH, Jae-Young 고재영] 209, Neungdong-ro 05006 서울시 광진구 능동로 209, SeoulGwangjin-guSeoul 05006;93, Daehak-ro 44610 울산시 남구 대학로 93, UlsanNam-guUlsan 44610;88, Olympic-ro 43-gil 05505 서울시 송파구 올림픽로43길 88, SeoulSongpa-guSeoul 05505 The present invention relates to a novel pharmaceutical composition for treating neurodegenerative diseases and, more particularly, to a pharmaceutical composition for treating neurodegenerative diseases, the composition comprising, as an active ingredient, an alloferon peptide having an amino acid sequence represented by SEQ ID NO: 1, a polynucleotide encoding the alloferon peptide, or an expression vector including the polynucleotide.

[KIM, Ho Jin 김호진, KWAK, Jung Won 곽정원, CHO, Byung Chul 조병철, LEE, Sang Wook 이상욱, JEONG, Chi Young 정치영, LIM, Young Kyung 임영경, HWANG, Ui Jung 황의중, CHOI, Sang Hyoun 최상현] 88, Olympic-ro 43-gil, 05505 서울시 송파구 올림픽로43길 88, SeoulSongpa-gu,Seoul 05505;93, Daehak-ro, 44610 울산시 남구 대학로 93, UlsanNam-gu,Ulsan 44610;323, Ilsan-ro, Ilsandong-gu, 10408 경기도 고양시 일산동구 일산로 323, Gyeonggi-doGoyang-si,Gyeonggi-do 10408;99, Daehak-ro 34134 대전시 유성구 대학로 99, DaejeonYuseong-guDaejeon 34134;75, Nowon-ro 01812 서울시 노원구 노원로 75, SeoulNowon-guSeoul 01812 The present invention relates to a method, a device, and a program for calculating a brachytherapy plan, and a brachytherapy apparatus. The method comprises: a step in which a computer obtains the number of radiation irradiation spots on the basis of radiation irradiation information (a radiation irradiation spot number obtaining step (S200)); a step in which the computer obtains target area information from a body model of a patient generated on the basis of medical image data of the patient (a target area information obtaining step (S400)); and a therapy plan calculating step (S600) in which the computer calculates, on the basis of the radiation irradiation information and the target area information, the radiation irradiation spots to which radiation is irradiated and the time length of irradiation to each radiation irradiation spot.

[KANG, Min Ji 강민지, LEE, Jiyoun 이지연, LEE, Ji Yu 이지유] 88 Olympic-ro 43-gil, 05505 서울특별시 송파구 올림픽로43길 88, SeoulSongpa-gu,Seoul 05505;93 Daehak-ro, 44610 울산광역시 남구 대학로 93, UlsanNam-gu,Ulsan 44610;2 Bomun-ro 34da-gil, 02844 서울특별시 성북구 보문로34다길 2, SeoulSeongbuk-gu,Seoul 02844 The compound represented by chemical formula 1, a stereoisomer thereof, a solvate thereof, a hydrate thereof, or a pharmaceutically acceptable salt thereof, according to one aspect, can be used as a prophylactic or therapeutic agent for degenerative diseases such as age-related macular degeneration (AMD) in which lack of HTRA1 activity is a factor in worsening the disease, cerebral amyloid angiopathy, hereditary stroke (CADASIL), and Alzheimer's disease (AD), and can be used as an adjuvant for efficiently and accurately screening an HTRA activity modulator without a change in temperature or addition of a substrate.