[HELLENDAHL, Beate, SCHLECKER, Rainer, ROEHL, Franz, ZIPPLIES, Matthias, RASCHACK, Manfred, HAFNER, Matthias] Carl-Bosch-Strasse 38 D-67056 Ludwigshafen;Sebastian-Kneipp-Strasse 17 D-6707 Schifferstadt;Suedring 8 D-6719 Bissersheim;Sebastian-Kneipp-Strasse 17 D-6707 Schifferstadt;Eichstrasse 36 D-6730 Neustadt;Donnersbergstrasse 7 D-6714 Weisenheim;Im Morchhof 24 D-6800 Manheim Medicament for oral administration which contains as active substance per individual dose, besides the customary galenic auxiliaries, 10 to 1000 mg of a compound of general formula (I) or (II) in which W is a carbonyl group or a single bond, R1 is a hydrogen atom or a group of the general formula R3CO in which R3 is a lower alkyl, lower alkoxy, mono lower alkylamino or di lower alkylamino group, R2 is an alkyl residue with 3 to 20 carbon atoms which may be branched or unbranched and contain 1 to 3 double bonds, a saturated cycle of 3 to 7 carbon atoms integrated into the chain or as substituent, or may be substituted by one or more aromatic rings or contain an oxygen or sulphur atom, as a racemate and as isolated enantiomers; or the addition salt thereof with a physiologically acceptable acid, and the active substances themselves insofar as they are novel.

[MUELLER THOMAS, ZIPPLIES MATTHIAS, AMMERMANN EBERHARD, LORENZ GISELA] DE;DE;DE;DE O.Z. 0050/41835 The present invention relates to bisguanidine derivatives of the formula I I where R1 and R2 are each, independently of one another, hydro gen, alkyl, alkenyl, alkynyl, alkoxyalkyl, haloalkenyl; or cycloalkyl which has 5 - 12 carbon atoms in the ring and may be substituted, or benzyl which may be substituted, with the proviso that only one of R1 and R2 can be hydrogen; or R1 and R2 are, together with the atoms which they substitute, a heterocyclic ring which may be substituted; X is CH2, O, a single bond, NH, N-alkyl or N benzyl whose phenyl ring may be substituted, n is 5 to 8, and their plant-compatible acid addition salts and their metal complexes and fungicides containing these compounds.

[Hubert Sauter, Matthias Zipplies, Norbert Goetz, Eberhard Ammermann, Ernst-Heinrich Pommer] DEX 6800 Mannheim 1 20 Neckarpromenade 4-trans-substituted cyclohexylamine derivatives of the formula where R.sup.1 is the group CR.sup.5 R.sup.6 R.sup.7, in which R.sup.5, R.sup.6 and R.sup.7 are hydrogen, unsubstituted or substituted alkyl, alkoxy, alkylthio or cycloalkyl, with the proviso that not more than one of the substituents R.sup.5, R.sup.6 and R.sup.7 may by hydrogen, or in which R.sup.6 and R.sup.7 together with the included carbon atom form a three-membered to six-membered carbocyclic aliphatic ring,salts thereof, and their use as fungicides.

[Sauter Hubert(20 Neckarpromenade,6800 Mannheim 1), Zipplies Matthias(1 Kastanienweg,6945 Hirschberg), Goetz Norbert(25 Schoefferstrasse,6520 Worms 1), Ammermann Eberhard(3 Sachsenstrasse,6700 Ludwigshafen), Pommer Ernst-Heinrich(7 Berliner Platz,6703 Limburgerhof)] 4-trans-substituted cyclohexylamine derivatives of the formula ##STR1## where R.sup.1 is the group CR.sup.5 R.sup.6 R.sup.7, in which R.sup.5, R.sup.6 and R.sup.7 are hydrogen, unsubstituted or substituted alkyl, alkoxy, alkylthio or cycloalkyl, with the proviso that not more than one of the substituents R.sup.5, R.sup.6 and R.sup.7 may by hydrogen, or in which R.sup.6 and R.sup.7 together with the included carbon atom form a three-membered to six-membered carbocyclic aliphatic ring, R.sup.2 and R.sup.3 are hydrogen, alkyl, alkenyl or alkynyl or cycloalkyl or cycloalkenyl, which in turn may be substituted, with the proviso that the sum of the carbon atoms and hetero atoms (O, S and halogen) of R.sup.2 and R.sup.3 together is not less than 8, R.sup.4 is hydrogen, alkyl, cycloalkyl or alkoxy, and m is 1 to 4, and the bond is a single or a double bond, salts thereof, and their use as fungicides.

[DRALLE-VOSS, Gabriele, STÖSSER, Michael, LANG, Siegfried, SAUPE, Thomas, ZIPPLIES, Matthias] D-67056 Ludwigshafen;Am Hinkelstein 33 D-64665 Alsbach-Hähnlein;Ulmenweg 9 D-67141 Neuhofen;Thomas-Mann-Strasse 22 D-67071 Ludwigshafen;Kressenwiesenweg 13/1 D-69207 Sanhausen;Eichstrasse 36 D-67434 Neustadt A process for purifying alkoxylated fats by treatment with a solid substance, characterized in that the solid substance used is a mixture of aluminium oxide and a silicate.

[KLUMPE, Markus, OSTROWSKI, Thomas, ZIPPLIES, Matthias] 67056 Ludwigshafen;Ernst-Barlach-Allee 8 68163 Mannheim;Sentastr. 6 68199 Mannheim;Eichstr. 36 67434 Neustadt What is proposed is a process for preparing polyether alcohols by reaction of one or more unsaturated starters having at least one active hydrogen atom per molecule with one or more alkylene oxides in the liquid phase, in the presence of a basic catalyst, in a reactor, which is characterized in that the metered addition of the one or more alkylene oxides into the reactor is effected in such a way that the concentration of unreacted alkylene oxide in the liquid reaction mixture in the reactor is increased as far as possible with increasing degree of addition of the alkylene oxide onto the starter, it being necessary at all times to meet the condition that the temperature at the end of a runaway reaction is at least 100 K below the onset temperature of the decomposition reaction of the liquid reaction mixture.

[ZIPPLIES MATTHIAS, BUSCHMANN ERNST, AMMERMANN EBERHARD, LORENZ GISELA] DE O.Z. 0050/40498 Phenylalkylamines of the formula I where n is 5, 6, 7, 8 or 9, m is 1, 2 or 3, R1 is methyl, halogen, substituted or unsubstituted aryl or substituted or unsubstituted phenoxy, and, when m is 2, two adjacent radicals R1 together denote the radical , X is oxygen, except when R1 is methyl, or the radical , R4 is isopropyl, tert-butyl or substituted or unsubstituted phenyl and R5 is H or OH, R2 and R3 are each hydrogen and, when X is oxygen, R2 and R3 additionally denote methyl or ethyl, and their plant-tolerated salts, and fungicides containing these compounds.

[ZIPPLIES MATTHIAS, SAUTER HUBERT, GOLD RANDALL E, AKERS ALAN, AMMERMANN EBERHARD, LORENZ GISELA] DE O.Z. 0050/40533 A fungicidal mixture of a) a compound of the formula I I, where Ra = tridecyl or 3-(p-tert-butyl-(phenyl)-2-methylpropyl, Rb = H, CH3 and X = O, CH2 and b) a compound of the formula II II, where R1 is substituted or unsubstituted phenyl, naphthyl, tetrahydronaphthyl, benzothiophenyl, benzofuranyl, anthracenyl, acenaphthenyl, hexahydroindacenyl, tetrahydrophenanthrenyl, stilbenyl or benzodioxolanyl, R2 is hydrogen or methyl, R3 is hydrogen, R4 is alkyl, cyclopropyl, haloalkyl or alkenyl, W is alkenylene, fluoroalkenylene or a single bond, R5 is substituted or unsubstituted phenyl, or is naphthyl, substituted or unsubstituted alkenyl, or alkynyl, where the radical may denote the acenaphthenyl radical and the radical may also be part of a heterocyclic ring.

[ZIPPLIES MATTHIAS, SAUTER HUBERT, ROEHL FRANZ, AMMERMANN EBERHARD, LORENZ GISELA] DE;DE;DE;DE;DE 0. Z . 0050/40924 Guanidines I (I) (A = C5-C12-cycloalkyl which may bear up to three further substituents;benzyl substituted in the para-position; R1, R2, R3 = H, C1-C4-alkyl; R4 = C5-C18-alkyl which may be interrupted by oxygen, C5-C18-alkenyl, C4-C18-alkynyl or phenyl-C1-C6-alkyl, and these groups may bear up to three further substituents and the phenyl moiety of the phenylalkyl may additionally bear a phenoxy group or up to three C2-C4-alkenyl, C1-C4-alkoxy-C1-C4-alkyl, C1-C6-alkyl or haloalkyl groups, C5-C6-cycloalkyl-Cl-C8-alkyl, where the ring may bear up to three further substituents; A = benzyl and R4 = C3-C4-alkyl which may be interrupted by oxygen, or C4-alkenyl, both of which may bear up to three further substituents; R3 + R4 = C5-C6-heterocycle which may bear up to three further substituents and may be interrupted by oxygen) and the salts I-HX and the metal complexes of I. The compounds I are suitable as fungicides.

[ZIPPLIES, Matthias, KEIL, Ortwin, HAGENMEYER, Veit, NOHR, Marcus] 67056 Ludwigshafen;Eichstr.36 67434 Neustadt;Friedhofweg 16 67283 Obrigheim;Defreggerstr. 24 67061 Ludwigshafen;Rathausstr. 31 67433 Neustadt The present invention relates to a method for controlling chemical engineering processes, wherein target value trajectories are provided for controlled variables, controlled variables and further state variables of the process are captured, control deviations are calculated, and controller manipulated variables are calculated therefrom by means of a control algorithm, pilot-control manipulated variables are determined, manipulated variables resulting from controller manipulated variables and pilot-control manipulated variables are calculated and adjusted in the process, wherein the structure of the control algorithm and/or of the pilot-control is changed as a function of control variables, further state variables and/or target trajectories. The invention further relates to a control device and a computer program for implementing said method.