Device for displaying small-size articles.
FR8216637A
FR
It is characterised in that it comprises a case 2 provided with a finger 3 comprising at least one optical fibre, a single one 6 of the ends 6, 7 of which penetrates into the said case 2 in which it is fixed in place in front of various optical systems positioned in this case so that their optical centres are aligned, both between themselves and, on the one hand, with the optical fibre and, on the other hand, with a means 9 for directly displaying the image, which means 9 is, for this purpose, carried by one of the faces of the case. Application to the display equipment industry. <IMAGE>
2-(ortho-Carboxyphenylamino)-6H-pyrimido[2,1-b]quinazol-6-one and its derivatives, process for preparing them and their therapeutic application
FR8216040A
SU
The invention relates to new substances and, in particular, it relates to 2-(ortho-carboxyphenylamino)-6H-pyrimido[2,1-b]quinazol-6-one and its derivatives, to a process for preparing them and to their pharmaceutical use. 2-(ortho-Carboxyphenylamino)-6H-pyrimido[2,1-b]quinazol-6-one has the following structural formula: <IMAGE> The derivatives correspond to the following structural formula: <IMAGE> in which A<+> is an alkali metal or a monoethanolamine or diethylamine residue, or to the following structural formula: <IMAGE> in which R is an OH or C1-4 alkoxy group, a group NHR', R' being H or a C1-4 alkyl group, or a phenyl or aralkyl group; A is a salt of an inorganic acid; or to the following structural formula: <IMAGE> in which R is a C1-4 alkoxy group or a group NHR', R' being a C1-4 alkyl group. The process for preparing 2-(ortho-carboxyphenylamino)-6H-pyrimido[2,1-b]quinazol-6-one and its derivatives consists, according to the invention, in reacting 2,4-dichloropyrimidine with anthranilic acid or anthranilic acid sodium salt or alternatively with substituted amides or esters of anthranilic acid, in an aqueous medium or in an organic solvent medium, at a temperature of 90 to 120 DEG C, the reaction mixture being maintained at this temperature for a period of 1 to 4 hours and the finished product being separated by a known process. The derivatives of the present invention have anti-inflammatory activity.